- Basic information
- CohesinDB ID: CDBP00414195
- Locus: chr21-18771838-18773092
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Data sourse: ENCSR000BTQ, GSE72082, GSE138405, GSE76893, GSE206145, GSE101921, ENCSR000EDE, ENCSR703TNG, GSE126990, GSE108869, ENCSR000ECS
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Cell type: MCF-7, RPE, HMEC, Hela-Kyoto, HeLa-S3
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 3% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.944
- Subunit: NIPBL,Rad21,SA2,Mau2,SMC3
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
30% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 92%,
"9_Het": 5%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, SKI, NCOA2, FOSL1, PGR, CEBPA, FOXA2, SIN3A, STAG2, SMAD3, MAFF, ELK4, FOXA1, DUX4, MEF2C, CDK9, HOXB13, TBP, ERG, HOXC5, RELA, ZXDC, CREBBP, ATF3, MYC, ONECUT1, SMARCA4, RAD21, LHX2, PBX4, ARNT, NRF1, GATA3, GABPA, STAT3, FOXM1, MAX, NRIP1, NKX3-1, CDK8, FOS, UBN1, NR3C1, CEBPB, ESRRA, TEAD1, TFAP2C, TCF7L2, NFE2L2, ETV1, CREB1, ESR1, TP53, TP73, GRHL2, JUN, ZHX2, TCF12, EP300, NUP98-HOXA9, MAFK, EHF, AR, GATA2, TRIM24, ZHX1, FLI1, JUND, BRD4, CTBP2, TEAD4, KMT2B, PDX1, AHR
- Target gene symbol (double-evidenced CRMs): .
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 16
- Related genes and loops