- Basic information
- CohesinDB ID: CDBP00414203
- Locus: chr21-18831843-18833594
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Data sourse: GSE138405, GSE126634, GSE206145, GSE152721, GSE85526, ENCSR000EDE, GSE68388, GSE126990, GSE108869, ENCSR000ECS
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Cell type: RPE, Hela-Kyoto, HEKn, HeLa-S3, HAP1, HuCC-T1
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 8% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.933
- Subunit: NIPBL,SA1,Rad21,SMC1,SA2,Mau2,SMC3
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
30% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 87%,
"7_Enh": 9%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: DAXX, FOSL1, SMC1A, NKX2-2, CHD2, MAFF, SMAD3, STAT1, FOXA1, ZNF205, HOXB13, SMARCC1, KDM1A, HOXC5, RELA, PAX6, CREBBP, ERG, JUNB, ATF3, MYC, GATA4, SMARCA4, ISL1, PRDM1, PBX4, NRF1, LHX2, RAD21, OTX2, GATA3, SMC3, GABPA, PROX1, STAT3, FOXM1, MAFB, TAL1, FOS, MAX, MITF, RCOR1, HAND2, MED1, CDX2, CHD7, NR3C1, CEBPB, KLF5, TEAD1, ETV1, TP53, TBX5, NFKB1, USF2, PHOX2B, JUN, MAFK, NIPBL, EP300, SPI1, HNF4A, AR, GATA6, TAF1, USF1, YAP1, GATA2, RFX5, ZHX1, FLI1, DEK, NCOR1, BRD4, JUND, TEAD4, TBX2, PDX1, ZNF316, FOSL2
- Target gene symbol (double-evidenced CRMs): TMPRSS15
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 20
- Related genes and loops