- Basic information
- CohesinDB ID: CDBP00414204
- Locus: chr21-18839975-18840750
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Data sourse: ENCSR000BLD, GSE104888, ENCSR230ZWH, GSE72082, GSE126634, ENCSR000BLY, GSE105028, GSE121355, GSE103477, GSE111537, GSE131606, GSE108869, GSE25021, ENCSR917QNE, ENCSR000BTU, GSE143937, GSE138405, GSE76893, GSE101921, GSE152721, GSE116344, ENCSR703TNG, GSE106870, GSE145327, GSE94872, ENCSR000BLS, GSE206145, GSE85526, ENCSR000ECE, ENCSR000BMY, ENCSR000EHX, GSE97394, GSE55407, GSE129526, GSE111913, ENCSR000EDE, GSE68388, GSE83726, GSE126990, GSE50893, ENCSR000ECS, GSE131577
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Cell type: MDM, RH4, GM2610, CVB-hiPSC, GM19240, Liver, HuCC-T1, H9-hESC, RPE, GM2630, HMEC, HEKn, Ishikawa, HeLa-S3, GM2255, K-562, GM18486, DKO, H1-hESC, SNYDER, GM12878, GM12891, GM2588, SK-N-SH, GM19239, RT-112, THP-1, HUES64, MCF-7, GM12892, Hela-Kyoto, HCT-116, HL-60, Hep-G2, MCF-10A, A-549, HUVEC, GM19238, OCI-AML-3, HAP1
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 18% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.556
- Subunit: SA1,Rad21,SMC1,SA2,SMC3
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CTCF binding site: CTCF
CTCF motif: True
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
30% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 76%,
"9_Het": 24%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: SMC1A, ZSCAN5D, POU5F1, TEAD4, DUX4, FOXA1, SRF, MEF2C, CDK9, HOXB13, TFAP4, RELA, ZBTB2, MYC, CDK6, RAD21, HIF1A, GATA3, MAX, ZNF143, CDK8, MED1, ARNTL, CEBPB, TRIM28, STAG1, ESR1, OCA2, NCOA1, MYOD1, CTCF, TCF12, USF1, BCL11A, AR, GATA2, IRF4, HSF1, NOTCH3, BRD4, JUND, TCF3, SMC1, SMC3, STAG2
- Target gene symbol (double-evidenced CRMs): TMPRSS15
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 5
- Related genes and loops