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Basic information

CohesinDB ID: CDBP00414216

Locus: chr21-18950211-18950629

Data sourse: GSE25021, GSE67783, GSE68388

Cell type: MCF-7, HSPC, HuCC-T1

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.967

Subunit: SA1,Rad21,SMC1

CTCF binding site: CTCF CTCF motif: False

Genomic location: TES

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 30% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 91%, "9_Het": 8%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: CBX5, ZNF660, SOX2, XBP1, FOXA1, CTCFL, ELF1, TRIM28, TEAD1, ETV1, NFE2L2, ESR1, CTCF, JUN, E2F6, IRF4, E2F1, SMC1, POU2F2, CHD8, BRD3, POU5F1, MYCN, CTBP1, DUX4, SRF, ERG, HOXC5, MYC, SMARCA4, RAD21, PROX1, NKX2-1, GABPA, IKZF1, NR3C1, CEBPB, ZBTB11, EBF3, GABPB1, SPI1, IRF1, GATA2, SMARCA5, ATF1, RUNX1, SMC1A, CBX1, CEBPA, NKX2-2, SIN3A, ZFX, SMAD3, ZNF654, TRIM22, SMARCC1, ZBTB2, NRF1, ARNT, PBX4, FOXM1, MED1, SCRT2, L3MBTL2, BCL11A, REST, SMC3, STAG2, STAG1, EBF1, WT1, CDK9, HOXB13, KDM1A, YY1, RELA, HIF1A, GATA3, MAX, ZNF143, HAND2, CEBPG, KDM5B, TP53, PHOX2B, AR, PAX3-FOXO1, ZBTB40, EGLN2, EGR1, NOTCH3, BRD4

Target gene symbol (double-evidenced CRMs): .

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 4

Related genes and loops

Related gene:

eachgene

Deatailed information for cohesin site CDBP00414216