- Basic information
- CohesinDB ID: CDBP00414260
- Locus: chr21-19321669-19322971
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Data sourse: ENCSR000BLD, GSE206145-GSE177045, GSE72082, GSE126634, ENCSR000BLY, ENCSR404BPV, GSE105028, GSE103477, GSE111537, GSE25021, GSE108869, ENCSR917QNE, ENCSR000BTU, ENCSR000DZP, ENCSR000EAC, ENCSR000BKV, GSE138405, GSE76893, GSE101921, GSE152721, ENCSR198ZYJ, GSE112028, GSE138105, ENCSR703TNG, GSE116344, GSE145327, ENCSR879KXD, ENCSR000ECE, ENCSR000EHX, GSE97394, ENCSR000BTQ, ENCSR000EDE, GSE126990, GSE50893, ENCSR000ECS, GSE131577
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Cell type: MDM, RH4, SLK, Liver, H9-hESC, Ishikawa, HeLa-S3, K-562, H1-hESC, GM12878, GM12891, SK-N-SH, HeLa-Tet-On, THP-1, HUES64, MCF-7, Hela-Kyoto, HL-60, MCF-10A, Neurons-H1, OCI-AML-3, HAP1
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 13% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.756
- Subunit: SA1,Rad21,SMC1,SA2,SMC3
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CTCF binding site: CTCF
CTCF motif: True
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
24% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 93%,
"9_Het": 4%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: PGR, FOXA2, POU5F1, SOX2, POU4F2, GTF2B, DUX4, FOXA1, ZNF823, SMARCC1, ERG, HOXC5, RELA, RUNX2, MYC, ARNT, HIF1A, PBX4, GRHL3, GATA3, GABPA, TAL1, STAT3, ZNF736, CEBPB, TEAD1, ESR1, TP73, GRHL2, SPI1, BCL11A, EP300, AR, GATA2, EGLN2, TEAD4, TFAP2C
- Target gene symbol (double-evidenced CRMs): .
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 13
- Related genes and loops
- Related gene:
- Related loop:
chr21:18275000-18300000~~chr21:19325000-19350000,
chr21:18500000-18525000~~chr21:19300000-19325000,
chr21:18800685-18802704~~chr21:19321159-19323544,
chr21:18825000-18850000~~chr21:19300000-19325000,
chr21:18950914-18953029~~chr21:19321763-19323259,
chr21:19300000-19325000~~chr21:20000000-20025000,
chr21:19300000-19325000~~chr21:20025000-20050000,
chr21:19300000-19325000~~chr21:20525000-20550000,
chr21:19300000-19325000~~chr21:20875000-20900000,
chr21:19321159-19323544~~chr21:20040110-20041964,
chr21:19321624-19323201~~chr21:20040107-20041944,
chr21:19321801-19323525~~chr21:19507255-19508484,
chr21:19325000-19350000~~chr21:19500000-19525000,
chr21:19325000-19350000~~chr21:20875000-20900000,