- Basic information
- CohesinDB ID: CDBP00414285
- Locus: chr21-19507539-19509004
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Data sourse: ENCSR000BLD, GSE206145-GSE177045, GSE104888, ENCSR230ZWH, ENCSR000FAD, GSE72082, GSE126634, GSE116868, ENCSR000EGW, ENCSR000BLY, GSE105028, GSE121355, GSE103477, GSE111537, GSE131606, GSE108869, GSE25021, ENCSR917QNE, GSE115602, ENCSR000BTU, GSE139435, ENCSR000EAC, GSE143937, ENCSR000BKV, GSE115250, GSE138405, GSE76893, GSE101921, GSE152721, GSE206145-NatGen2015, GSE112028, GSE130135, ENCSR703TNG, GSE106870, GSE116344, GSE138105, GSE145327, GSE94872, ENCSR000BLS, ENCSR000EHW, ENCSR000ECE, ENCSR000EHX, GSE97394, GSE55407, ENCSR000BTQ, GSE105004, GSE131956, GSE110061, GSE129526, ENCSR000EDE, ENCSR153HNT, GSE68388, GSE83726, GSE126990, GSE50893, ENCSR000ECS, GSE131577
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Cell type: MDM, RH4, GM2610, SLK, CVI-hiPSC, Liver, TC-32, HuCC-T1, H9-hESC, GM2630, Fibroblast, Ishikawa, HeLa-S3, GM2255, K-562, GM18486, DKO, H1-hESC, SNYDER, Leukemia-SEM, MB157, GM12878, GM12891, GM2588, GBM39, SK-N-SH, HeLa-Tet-On, THP-1, HUES64, MCF-7, GM12892, Hela-Kyoto, HCT-116, HL-60, HEK293T, Hep-G2, MCF-10A, HUVEC, GM19238, HeLa, OCI-AML-3, HAP1
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 25% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.533
- Subunit: SA1,Rad21,SMC1,SA2,SMC3
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
26% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 69%,
"9_Het": 28%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, CBX5, SMC1A, CBX1, PGR, MYCN, CHD8, ZSCAN5D, SIN3A, ZFX, STAG2, XBP1, GTF2B, CEBPA, ZSCAN5A, STAT1, FOXA1, SRF, MEF2C, PBX2, TRIM22, CDK9, TBP, ERG, YY1, RELA, HDGF, CREBBP, IRF2, MYC, SMARCA4, RAD21, GRHL3, HIF1A, GABPA, ZNF143, IKZF1, NFE2, CDK8, MED1, VDR, JMJD1C, CEBPB, GFI1B, ELF1, TRIM28, NCOA3, TFAP2C, MYB, STAG1, KDM5B, ESR1, PKNOX1, EZH2, MLL, MYOD1, STAT5A, CTCF, BCL11A, SPI1, TBX21, AR, DPF2, REST, GATAD2B, IRF4, TRIM24, NOTCH3, BRD4, IKZF2, RELB, SMC1, SMC3, ZNF24, MLLT1, AHR, EED
- Target gene symbol (double-evidenced CRMs): TMPRSS15
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 13
- Related genes and loops
- Related gene:
ENSG00000154646,
- Related loop:
chr21:18275000-18300000~~chr21:19500000-19525000,
chr21:18500000-18525000~~chr21:19500000-19525000,
chr21:18800000-18825000~~chr21:19500000-19525000,
chr21:18950000-18975000~~chr21:19500000-19525000,
chr21:18950724-18953125~~chr21:19506984-19508943,
chr21:18950733-18953097~~chr21:19507036-19509059,
chr21:19321801-19323525~~chr21:19507255-19508484,
chr21:19325000-19350000~~chr21:19500000-19525000,
chr21:19500000-19525000~~chr21:19600000-19625000,
chr21:19500000-19525000~~chr21:19675000-19700000,
chr21:19500000-19525000~~chr21:19775000-19800000,
chr21:19500000-19525000~~chr21:20425000-20450000,
chr21:19500000-19525000~~chr21:20550000-20575000,
chr21:19500000-19525000~~chr21:20875000-20900000,
chr21:19507043-19508857~~chr21:20040107-20041944,