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Basic information

CohesinDB ID: CDBP00414291

Locus: chr21-19529050-19529358

Data sourse: ENCSR000BTQ, GSE72082, GSE76893, ENCSR703TNG, GSE25021

Cell type: MCF-7

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 2% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.989

Subunit: NIPBL,SA1,Rad21,SMC1

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intergenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: False Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 26% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 90%, "9_Het": 7%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: PGR, MEIS2, FOXA1, PBX2, TFAP4, BMI1, NFIC, WDHD1, MECOM, SMARCE1, DPF1, TEAD1, ZNF217, ESR1, LMO2, TCF12, EP300, MNT, DPF2, TEAD4, TFAP2C, MYCN, CTBP1, ERG, MYC, RFX1, ARID1B, RAD21, GRHL3, FOXK2, NR3C1, ESRRA, GRHL2, TRPS1, ZHX2, SPI1, HDAC2, GATA2, GATAD2B, ZIM3, RUNX1, SMC1A, CBX1, HDAC1, CEBPA, SIN3A, ZXDC, CREBBP, GR, ARNT, FOXM1, CBFA2T3, FOS, CDK8, MED1, ZMYM3, L3MBTL2, EVI1, USF1, NIPBL, TFAP2A, CTBP2, MBD2, BCOR, STAG1, FOXA2, MEIS1, RELA, NEUROD1, ISL1, HIF1A, GATA3, TAL1, MAX, NRIP1, HAND2, NCOA3, NR2F1, TCF7L2, KDM5B, PKNOX1, AR, EGLN2, NCOR1, BRD4, CUX1, ZNF24, AHR

Target gene symbol (double-evidenced CRMs): .

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 2

Related genes and loops

Related gene:

eachgene

Deatailed information for cohesin site CDBP00414291