- Basic information
- CohesinDB ID: CDBP00414352
- Locus: chr21-19999349-20000214
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Data sourse: GSE38395, ENCSR000EAC, GSE67783, ENCSR879KXD, ENCSR153HNT, GSE103477, GSE111537, GSE50893
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Cell type: THP-1, GM12878, hLCL, GM19238, K-562, OCI-AML-3, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.922
- Subunit: NIPBL,SA1,Rad21,SA2
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
18% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 64%,
"9_Het": 30%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, NFATC3, SMC1A, MEF2B, CBX3, TBL1X, CEBPA, LDB1, SOX2, ZFX, RBBP5, XBP1, MTA2, ZBTB48, WT1, FOXA1, MEF2C, RBFOX2, PBX2, TRIM22, CDK9, ERG, TARDBP, LYL1, ATF3, CHAMP1, GATA4, ARID1B, HNRNPUL1, SP140, ARNT, ATF2, BATF, TAL1, MAX, NR2C1, GATA1, IKZF1, CDK8, FOS, CEBPB, NR2F2, TRIM28, CEBPD, MYB, LMO2, PKNOX1, SETDB1, PHOX2B, CTCF, TCF12, BCL11A, KLF1, EP300, SPI1, DPF2, RXR, ZBTB7A, E2F6, TRIM24, GATA2, ATF7, FLI1, RNF2, NR2C2, BRD4, JUND, TCF3, RAD51, RELB, TEAD4, KMT2B, MLLT1
- Target gene symbol (double-evidenced CRMs): .
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 20
- Related genes and loops
- Related gene:
- Related loop:
chr21:18950000-18975000~~chr21:20000000-20025000,
chr21:19300000-19325000~~chr21:20000000-20025000,
chr21:19375000-19400000~~chr21:20000000-20025000,
chr21:19550000-19575000~~chr21:20000000-20025000,
chr21:19600000-19625000~~chr21:20000000-20025000,
chr21:19725000-19750000~~chr21:20000000-20025000,
chr21:19875000-19900000~~chr21:20000000-20025000,
chr21:19900000-19925000~~chr21:20000000-20025000,
chr21:19975000-20000000~~chr21:20525000-20550000,
chr21:20000000-20025000~~chr21:20175000-20200000,
chr21:20000000-20025000~~chr21:20200000-20225000,
chr21:20000000-20025000~~chr21:20225000-20250000,
chr21:20000000-20025000~~chr21:20300000-20325000,
chr21:20000000-20025000~~chr21:20425000-20450000,
chr21:20000000-20025000~~chr21:20625000-20650000,
chr21:20000000-20025000~~chr21:20850000-20875000,