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Basic information

CohesinDB ID: CDBP00414361

Locus: chr21-20037384-20038205

Data sourse: ENCSR000BLD, GSE72082, GSE126634, ENCSR000BLY, GSE105028, GSE103477, GSE111537, GSE25021, GSE108869, GSE67783, ENCSR000BKV, GSE86191, GSE138405, GSE116344, ENCSR703TNG, GSE106870, GSE145327, ENCSR000ECE, GSE97394, GSE55407, ENCSR000BTQ, GSE111913, GSE83726, GSE50893, GSE38411

Cell type: RH4, GM2610, CVI-hiPSC, H9-hESC, HeLa-S3, K-562, BCBL-1, H1-hESC, SNYDER, GM2588, SK-N-SH, RT-112, HAP1, THP-1, HUES64, MCF-7, Hela-Kyoto, HCT-116, GM19238, OCI-AML-3, HSPC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 9% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.767

Subunit: SA1,Rad21,SA2,SMC1

CTCF binding site: CTCF CTCF motif: True

Genomic location: Intergenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 17% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 81%, "9_Het": 19%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: CEBPB, SMC1A, ATF3, TRIM28, RAD21, ZFX, KDM5B, ESR1, SMC1, ZBTB33, SMC3, CTCF, STAG1

Target gene symbol (double-evidenced CRMs): TMPRSS15

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 7

Related genes and loops

Related gene: ENSG00000154646,

eachgene

Deatailed information for cohesin site CDBP00414361