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Basic information

CohesinDB ID: CDBP00414364

Locus: chr21-20040481-20041267

Data sourse: ENCSR000BLD, GSE206145-GSE177045, ENCSR230ZWH, GSE72082, GSE126634, ENCSR000BLY, ENCSR404BPV, GSE105028, GSE103477, GSE111537, GSE25021, GSE108869, GSE115602, ENCSR917QNE, ENCSR000BTU, ENCSR000EAC, GSE138405, GSE76893, GSE152721, ENCSR198ZYJ, GSE112028, GSE138105, ENCSR703TNG, GSE116344, GSE145327, GSE94872, ENCSR879KXD, ENCSR000ECE, ENCSR000EHX, GSE97394, ENCSR000BTQ, ENCSR000EDE, GSE126990, GSE50893, ENCSR000ECS

Cell type: MDM, RH4, GM2610, SLK, Liver, H9-hESC, GM2630, Ishikawa, HeLa-S3, K-562, H1-hESC, SNYDER, GM12878, GM2588, GM12891, SK-N-SH, HeLa-Tet-On, THP-1, HUES64, MCF-7, Hela-Kyoto, Neurons-H1, HUVEC, GM19238, OCI-AML-3, HAP1

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 17% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.711

Subunit: SA1,Rad21,SMC1,SA2,SMC3

CTCF binding site: CTCF CTCF motif: True

Genomic location: Intergenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 17% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 86%, "9_Het": 9%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: SMC1A, FOXA2, POU5F1, STAG2, FOXA1, HOXB13, ERG, ZBTB2, MYC, CTCFL, RAD21, DAXX, ARNT, TAL1, MAX, NR2C1, GATA1, NR2F6, NR2F2, NR2F1, SMAD1, KDM5B, ESR1, CTCF, USF1, BCL11A, NR4A1, AR, REST, EGLN2, RAD51, BRD4, SMC1, SMC3, STAG1

Target gene symbol (double-evidenced CRMs): TMPRSS15

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 6

Related genes and loops

Related gene: ENSG00000154646,

eachgene

Deatailed information for cohesin site CDBP00414364