- Basic information
- CohesinDB ID: CDBP00414393
- Locus: chr21-20258435-20258956
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Data sourse: GSE143937, ENCSR000BKV, ENCSR000EGW, ENCSR879KXD, GSE73207
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Cell type: K-562, TF-1
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: SMC3,Rad21
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: TSS,TES
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: False
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
23% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 72%,
"7_Enh": 13%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOXO1, FOSL1, CBX5, SOX2, MEIS2, FOXA1, PBX2, HDGF, LYL1, ATF3, NFIC, CHD7, MECOM, SMARCE1, HDAC3, JMJD1C, ELF1, TRIM28, BCLAF1, ETV1, TEAD1, NFE2L2, SMAD5, LMO2, MLL, ZFP91, JUN, TCF12, CTCF, EP300, E4F1, DPF2, PAX8, TRIM24, CREB3, SOX6, RAD51, TEAD4, EHMT2, EED, RUNX1T1, ID3, TOP2A, CTBP1, MTA2, STAT1, NBN, ARID3A, PHB2, TBP, ERG, SMARCC2, MYC, SMARCA4, EOMES, ARID1B, RAD21, RXRA, FOXK2, IKZF1, LEF1, RCOR1, NR2F6, NFRKB, NFE2, ZNF639, NR3C1, CEBPB, KMT2A, TBL1XR1, GABPB1, SPI1, HDAC2, GATA2, ZSCAN29, EP400, ATF1, CC2D1A, RUNX1, MAFG, HDAC1, CEBPA, LDB1, ZMIZ1, ZNF18, PRDM10, SMARCC1, MEF2A, MYBL2, BRD9, GATA4, ARNT, ATF2, ZEB2, HMBOX1, NFYA, FOXM1, CBFA2T3, NR2C1, CDK8, GMEB1, PML, CEBPD, MYB, NCOA1, L3MBTL2, SETDB1, EVI1, STAT5A, KLF16, USF1, BCL11A, SP1, REST, ZBTB7A, CCNT2, ATF7, AFF1, TCF3, MBD2, STAT2, MLLT1, NFATC3, SKI, CBFA2T2, CBX3, MTA3, RBBP5, CREM, MEIS1, FOXA2, FOXF1, ZBTB33, KDM1A, YY1, TARDBP, ZNF148, NEUROD1, CHAMP1, TAL1, MAX, GATA1, MTA1, ZNF592, GFI1B, NR2F2, NR2F1, PKNOX1, TBX21, BHLHE40, ZBTB16, ZBTB40, MYNN, RNF2, NCOR1, BRD4, ILF3, JUND, ZNF24, AHR
- Target gene symbol (double-evidenced CRMs): .
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 3
- Related genes and loops