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Basic information

CohesinDB ID: CDBP00414427

Locus: chr21-20570796-20571435

Data sourse: ENCSR000BLD, ENCSR230ZWH, GSE72082, ENCSR000BLY, GSE105028, GSE103477, GSE111537, GSE25021, GSE108869, ENCSR917QNE, ENCSR000BTU, GSE36578, GSE101921, ENCSR198ZYJ, GSE112028, GSE116344, GSE106870, GSE145327, ENCSR000ECE, GSE97394, ENCSR000BTQ, ENCSR000EDE, GSE68388, GSE83726, GSE50893, GSE64758

Cell type: MDM, RH4, GM2610, CVB-hiPSC, CVI-hiPSC, Liver, HuCC-T1, H9-hESC, GM2630, Ishikawa, HeLa-S3, H1-hESC, SK-N-SH, HeLa-Tet-On, THP-1, HUES64, MCF-7, MCF-10A, Neurons-H1, BGO3, OCI-AML-3

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 10% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.767

Subunit: NIPBL,SA1,Rad21,SMC1,SA2

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intergenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 25% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 89%, "9_Het": 6%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: FOSL1, CBFA2T2, CHD8, CBX1, NANOG, POU5F1, CBX5, ZNF207, SOX2, POU2F2, POU4F2, XBP1, GTF2B, SMAD3, STAT1, PBX2, KDM1A, ERG, RELA, YY1, GATA4, KDM4A, ARID1B, CHD7, RAD21, ZFP36, ARNT, ATF2, SMC3, GABPA, TAL1, CBFA2T3, MAX, GATA1, ZNF143, RCOR1, CEBPD, TRIM28, CREB1, SMAD1, TP53, ESR1, NFKB1, CTCF, TCF12, T, BCL11A, TFAP2A, NIPBL, EP300, HDAC2, REST, ZBTB7A, GATA2, RBM25, HSF1, CTBP2, BRD4, BCOR, FOXP1, JUND, SMC1, TEAD4, STAG1, TFAP2C

Target gene symbol (double-evidenced CRMs): .

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 11

Related genes and loops

Related gene:

eachgene

Deatailed information for cohesin site CDBP00414427