- Basic information
- CohesinDB ID: CDBP00414448
- Locus: chr21-20738868-20740209
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Data sourse: ENCSR000BLD, GSE206145-GSE177045, ENCSR230ZWH, GSE72082, GSE126634, ENCSR000BLY, GSE105028, GSE103477, GSE111537, GSE25021, GSE108869, GSE115602, ENCSR917QNE, ENCSR000BKV, GSE115250, GSE138405, GSE76893, GSE152721, GSE116344, ENCSR703TNG, GSE106870, GSE145327, ENCSR000EHW, ENCSR000ECE, ENCSR000EHX, GSE97394, GSE55407, ENCSR000BTQ, ENCSR153HNT, GSE68388, GSE83726, GSE126990
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Cell type: MCF-7, H1-hESC, Hela-Kyoto, RH4, THP-1, CVB-hiPSC, HeLa-S3, HUES64, SK-N-SH, K-562, Liver, TC-32, OCI-AML-3, HAP1, HuCC-T1, H9-hESC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 12% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.822
- Subunit: SA1,Rad21,SMC1,SA2,SMC3
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: False
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
25% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 75%,
"9_Het": 20%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: NANOG, SMC1A, POU2F2, CBX3, POU5F1, CHD8, PGR, ZFX, POU4F2, XBP1, SMAD3, STAT1, FOXA1, SRF, ERG, RELA, NOTCH1, RAD21, PRDM1, GRHL3, HIF1A, GABPA, TAL1, MAX, ZNF143, CEBPB, NCOA3, ELF1, TRIM28, CREB1, ETV1, SMAD1, KDM5B, LMO2, ESR1, STAT5A, GABPB1, CTCF, SPI1, GSPT2, AR, HDAC2, REST, TRIM24, NOTCH3, BRD4, SMC3, STAG1, TFAP2C
- Target gene symbol (double-evidenced CRMs): .
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 16
- Related genes and loops