- Basic information
- CohesinDB ID: CDBP00414463
- Locus: chr21-20856985-20857310
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Data sourse: GSE206145-GSE177045, ENCSR230ZWH, ENCSR917QNE, GSE68388, GSE25021, GSE73207
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Cell type: MCF-7, Liver, TF-1, HuCC-T1
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.956
- Subunit: SA1,Rad21,SMC1,Mau2,SMC3
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: False
- Compartment:
25% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 92%,
"9_Het": 5%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: PGR, MEIS2, FOXA1, PBX2, ATF3, NFIC, SMARCE1, HDAC3, TEAD1, ELF1, ETV1, NFE2L2, LMO2, ESR1, CTCF, TCF12, BAF155, EP300, GATA6, SOX5, DPF2, TRIM24, SOX6, E2F1, TEAD4, PDX1, TFAP2C, NANOG, CTBP1, MTA2, ERF, STAT1, ARID3A, HNF4G, ERG, ASCL1, MYC, SMARCA4, EOMES, ARID1B, RAD21, RXRA, NKX2-1, GABPA, STAT3, NKX3-1, LEF1, RCOR1, NR3C1, ESRRA, CEBPB, CREB1, TBL1XR1, GRHL2, TRPS1, HES1, HDAC2, GATA2, FLI1, ATF1, CC2D1A, RUNX1, HDAC1, NKX2-2, CEBPA, SIN3A, SOX13, SMAD3, ZMIZ1, CREBBP, GATA4, ARNT, PBX4, SOX11, SMAD4, CBFA2T3, FOXM1, PML, CEBPD, MYB, PIAS1, NCOA1, STAT5A, KLF16, SP1, BCL11A, HNF4A, ZBTB7A, CCNT2, POU2F3, ASH2L, CTBP2, AFF1, FOXP1, SMC3, STAG1, CBFA2T2, FOXA2, CREM, ZBTB33, HOXB13, ZNF318, KDM1A, YY1, RELA, CHAMP1, HIF1A, GATA3, TAL1, MAX, GATA1, TLE3, GFI1B, PKNOX1, T, BHLHE40, AR, EGR1, MYNN, RNF2, NCOR1, BRD4, ILF3, HSF1, JUND, AHR
- Target gene symbol (double-evidenced CRMs): .
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 4
- Related genes and loops