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Basic information

CohesinDB ID: CDBP00414475

Locus: chr21-20971051-20972166

Data sourse: ENCSR000BLD, ShirahigeLab-GSE177045, ENCSR230ZWH, ENCSR000FAD, GSE72082, GSE126634, ENCSR000EGW, ENCSR000BLY, ENCSR404BPV, GSE105028, GSE121355, GSE103477, GSE111537, GSE25021, GSE108869, ENCSR000EDW, ENCSR000BUC, ENCSR917QNE, ENCSR000EFJ, ENCSR000BTU, GSE115602, ENCSR000DZP, ENCSR000EAC, GSE143937, ENCSR000BKV, GSE115250, GSE138405, GSE93080, GSE76893, GSE101921, GSE152721, GSE51234, ShirahigeLab-NatGen2015, ENCSR198ZYJ, GSE112028, GSE130135, ENCSR703TNG, GSE116344, GSE138105, GSE145327, GSE94872, ENCSR000EEG, GSE115248, ENCSR193NSH, ENCSR879KXD, ENCSR000BLS, ENCSR000EHW, ShirahigeLab, ENCSR000ECE, ENCSR000BMY, ENCSR000EHX, GSE97394, GSE55407, ENCSR000BTQ, GSE105004, ENCSR167MTG, ENCSR944ZCT, GSE131956, GSE110061, GSE129526, ENCSR000HPG, ENCSR335RKQ, ENCSR000EDE, GSE68388, GSE126990, GSE50893, ENCSR000ECS, GSE131577

Cell type: MDM, RH4, GM2610, SLK, Liver, GP5d, TC-32, HuCC-T1, H9-hESC, RPE, GM2630, Fibroblast, Ishikawa, Kelly, HeLa-S3, IMR-90, K-562, GM18486, H1-hESC, SNYDER, GM12878, GM12891, GM2588, GBM39, SK-N-SH, HeLa-Tet-On, THP-1, HUES64, MCF-7, GM12892, Hela-Kyoto, HCT-116, HL-60, HEK293T, Hep-G2, MCF-10A, Neurons-H1, A-549, HUVEC, GM19238, HeLa, TC-71, OCI-AML-3, HAP1

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 33% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.500

Subunit: SA1,Rad21,SMC1,SMC3ac,SA2,SMC3

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intergenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 25% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 88%, "5_TxWk": 7%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: RUNX1, NANOG, SMC1A, PGR, CEBPA, POU5F1, NKX2-2, TOP2A, ZNF660, NME2, STAG2, ZNF44, SOX2, FOXA1, SRF, TRIM22, HOXB13, HOXC5, ERG, ZBTB2, ZNF384, JUNB, ATF3, RAD21, HIF1A, OTX2, ATF2, BATF3, NKX2-1, STAT3, FOS, TLE3, PDX1, CREB1, PIAS1, SMAD1, ESR1, TP53, CTCF, JUN, BCL11A, BAF155, AR, ZNF257, GATA2, IRF4, RFX5, ATF7, JUND, SMC1, SMC3, ATF1, STAG1

Target gene symbol (double-evidenced CRMs): .

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 6

Related genes and loops

Related gene:

eachgene

Deatailed information for cohesin site CDBP00414475