Browse_each

Basic information

CohesinDB ID: CDBP00414482

Locus: chr21-20995936-20996190

Data sourse: ENCSR000BLD, GSE25021, GSE120943, GSE98367

Cell type: MCF-7, H1-hESC, Monocytes, Macrophage

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 2% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.956

Subunit: SA1,Rad21,SMC1

CTCF binding site: CTCF CTCF motif: False

Genomic location: TSS

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 25% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "14_ReprPCWk": 51%, "15_Quies": 42%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: FOXO1, TRIM25, PGR, CBX5, FANCL, ZNF660, HMGN3, MEIS2, SOX2, XBP1, NME2, KDM4B, FOXA1, SUZ12, RBFOX2, PBX2, RING1B, UBTF, ZFHX2, KDM3A, HNRNPK, TFAP4, MEN1, ATF3, CTCFL, CHD7, ZBTB44, PRDM1, ZNF207, ATF4, CBFB, EGR1, TP63, MITF, SFPQ, JMJD1C, TEAD1, TRIM28, ELF1, RBM39, ETV1, NFE2L2, LMO2, ESR1, OCA2, ZNF217, PITX3, MED26, SAP30, CTCF, JUN, TCF12, EP300, BAF155, KLF1, MNT, RYBP, PAX8, SOX4, E2F6, DMAP1, TRIM24, IRF4, RFX5, SOX6, E2F4, PRKDC, E2F1, SMC1, TEAD4, KMT2B, GTF2F1, PDX1, TFAP2C, EED, RBPJ, JARID2, POU2F2, CHD8, BRD1, ZSCAN5D, ZNF263, MYCN, POU5F1, ID3, RUNX1T1, CTBP1, CDK7, BRD3, ZBTB48, TOP2A, STAT1, MLLT3, SRF, DDX5, ERG2, TBP, HNF4G, HOXC5, ERG, OGG1, ETS1, MYC, SMARCA4, KDM4A, HOMEZ, RAD21, FOXP2, GRHL3, TOP1, PROX1, NKX2-1, RXRA, GABPA, STAT3, ZNF614, XRCC5, NKX3-1, PRDM14, RCOR1, NFE2, NR3C1, CEBPB, KMT2A, CREB1, EZH2, GRHL2, EBF3, TRPS1, GABPB1, PHF8, SPI1, ZNF257, PCBP1, HDAC2, GATA2, MXD3, SIX2, FLI1, GTF3C5, MXI1, HCFC1R1, MRTFB, NCOA2, PTBP1, RUNX1, THAP11, SMC1A, CBX1, HDAC1, EZH2phosphoT487, SIRT6, CEBPA, SIN3A, ZFX, ZNF534, FIP1L1, ZMYM2, SMAD3, SOX13, ZFP37, TET2, NMYC, ERG3, CBX8, ZNF654, TRIM22, SMARCC1, CREBBP, RARA, PRPF4, ZXDC, TAF15, NOTCH1, RUNX2, ZSCAN30, ZBTB2, GR, PBX4, DAXX, BACH1, ARNT, ZNF48, PRDM9, SMAD4, PBX3, NCAPH2, MAFB, FOS, CDK8, CHD1, MED1, CSNK2A1, TEAD3, ZEB1, KDM6B, MYB, PML, PIAS1, SMAD1, VEZF1, TAF7, KLF9, NCOA1, L3MBTL2, GTF3C2, SETDB1, STAT5A, KLF16, USF1, MAFK, TFAP2A, BCL11A, NR4A1, ARID2, REST, ZBTB7A, ZNF479, CCNT2, RBM25, POU2F3, ATF7, ASH2L, HNRNPLL, CTBP2, NKX2-2, BCOR, MBD2, FOXP1, TCF3, AATF, SMC3, STAG1, STAG2, HMGB1, MLLT1, CXXC4, NELFA, TRP47, CBFA2T2, FOXA2, TBL1X, RBBP5, MTA3, CHD2, AGO1, CBX3, ZNF44, CREM, WT1, GTF2B, ESR2, ZBTB33, MEF2C, CDK9, ZNF580, ZKSCAN1, HOXB13, KDM1A, YY1, RELA, TARDBP, NEUROD1, CHAMP1, ZNF610, SP140, ZFP36, HIF1A, PCGF1, OTX2, GATA3, ZNF519, TAL1, MAX, NRIP1, GATA1, AGO2, ZNF143, HAND2, CBX2, PLAG1, CEBPG, BCL6, SP7, NCOA3, KLF4, NR2F1, NEUROG2, KDM5B, TP53, PKNOX1, ZNF334, ZSCAN22, ELF3, NANOG, BRD2, ARRB1, TBX21, BHLHE40, AR, TAF1, ZBTB40, EGLN2, ZBTB42, HEXIM1, RB1, TFIIIC, HSF1, RNF2, NOTCH3, BRD4, ZBTB26, JUND, CLOCK, CUX1, MAZ, TBX2, ZNF24, ADNP, AHR

Target gene symbol (double-evidenced CRMs): NCAM2

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 4

Related genes and loops

Related gene: ENSG00000154654,

eachgene

Deatailed information for cohesin site CDBP00414482