- Basic information
- CohesinDB ID: CDBP00414485
- Locus: chr21-21007581-21007949
-
Data sourse: ShirahigeLab-GSE177045, GSE72082, GSE68388, GSE165895
-
Cell type: MCF-7, HuCC-T1, HFFc6
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: Mau2,Rad21,SMC1
-
CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
27% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
-
Chromatin annotation:
"15_Quies": 84%,
"7_Enh": 9%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: RUNX1, ZNF496, FOXA2, ESR2, FOXA1, HOXB13, ERG, RELA, CREBBP, BRG1, PBX4, GATA3, NRIP1, NKX3-1, CHD1, TLE3, CREB1, PIAS1, ESR1, GRHL2, BAF155, AR, GATA6, GATA2, ARID1A, BRD4, CTBP2, FOXP1, AHR
- Target gene symbol (double-evidenced CRMs): NCAM2
- Function elements
- Human SNPs: Blood_protein_levels
- Number of somatic mutations (coding): 3
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000154654,
- Related loop:
chr21:21000000-21025000~~chr21:21100000-21125000,
chr21:21000000-21025000~~chr21:21150000-21175000,
chr21:21000000-21025000~~chr21:21200000-21225000,
chr21:21000000-21025000~~chr21:21275000-21300000,
chr21:21000000-21025000~~chr21:21300000-21325000,
chr21:21000000-21025000~~chr21:21325000-21350000,
chr21:21000000-21025000~~chr21:21350000-21375000,
chr21:21000000-21025000~~chr21:21375000-21400000,
chr21:21000000-21025000~~chr21:21650000-21675000,
chr21:21000000-21025000~~chr21:21675000-21700000,
chr21:21000000-21025000~~chr21:21750000-21775000,
chr21:21000000-21025000~~chr21:21900000-21925000,
chr21:21000000-21025000~~chr21:21925000-21950000,
chr21:21000000-21025000~~chr21:22100000-22125000,
chr21:21000000-21025000~~chr21:22775000-22800000,
chr21:21000000-21025000~~chr21:23150000-23175000,
chr21:21000000-21025000~~chr21:23375000-23400000,
chr21:21000000-21025000~~chr21:23400000-23425000,
chr21:21000000-21025000~~chr21:23675000-23700000,
chr21:21000000-21025000~~chr21:23950000-23975000,
chr21:21000000-21025000~~chr21:24500000-24525000,
chr21:21000000-21025000~~chr21:24875000-24900000,
chr21:21000000-21025000~~chr21:25000000-25025000,
chr21:21000000-21025000~~chr21:25025000-25050000,
chr21:21000000-21025000~~chr21:25300000-25325000,
chr21:21000000-21025000~~chr21:25325000-25350000,
chr21:21000000-21025000~~chr21:25375000-25400000,
chr21:21003038-21004640~~chr21:21101289-21102786,
chr21:21003051-21004829~~chr21:21101340-21102914,
chr21:21003058-21004646~~chr21:21688144-21689874,
chr21:21003058-21004646~~chr21:21920972-21923111,
chr21:21003089-21004639~~chr21:21101203-21103013,
chr21:21003101-21004721~~chr21:21101174-21102946,
chr21:21003101-21004721~~chr21:21688167-21689840,
chr21:21003101-21004721~~chr21:21920938-21922813,
chr21:21003128-21004732~~chr21:21372936-21375055,
chr21:21003137-21004624~~chr21:21688096-21689849,
chr21:21003151-21004646~~chr21:21372959-21374950,
chr21:21003151-21004646~~chr21:21687901-21690144,
chr21:21003151-21004646~~chr21:21920910-21923131,
chr21:21003163-21004635~~chr21:21687914-21690146,
chr21:21003242-21004641~~chr21:21101303-21102752,
chr21:21003264-21004580~~chr21:21687914-21690120,
chr21:21003266-21004597~~chr21:21101164-21102785,
chr21:21003271-21004562~~chr21:21101398-21102732,
chr21:21003276-21004585~~chr21:21101357-21102787,
chr21:21003301-21004546~~chr21:21921038-21922969,