- Basic information
- CohesinDB ID: CDBP00414493
- Locus: chr21-21051098-21051509
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Data sourse: GSE103477, GSE120943, GSE98367
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Cell type: THP-1, Monocytes, Macrophage
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: Rad21,SMC1
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
27% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 88%,
"7_Enh": 5%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, SKI, PGR, SMC1A, ZNF316, CEBPA, FOXA2, MAFG, MEIS1, MEIS2, ZBTB48, MAFF, STAT1, FOXA1, MLLT3, MEF2C, DDX5, CDK9, PBX2, HOXB13, ERG, KDM1A, RELA, ONECUT1, SMARCA4, RAD21, ARNT, HIF1A, GRHL3, TCF4, BHLHE22, GATA3, OTX2, GABPA, BATF, STAT3, MECOM, SPIB, GATA1, CDK8, IKZF1, ZNF736, MED1, VDR, JMJD1C, CEBPB, TRIM28, KMT2A, MYB, PIAS1, TCF7L2, SMAD1, LMO2, ESR1, C11orf30, EVI1, TRPS1, PHOX2B, CTCF, TCF12, MAFK, SPI1, BCL11A, NR4A1, AR, IRF1, GATA2, EGLN2, TRIM24, IRF4, BRD4, TCF3, ZNF766, ZIM3, NCOR2, MLLT1, AHR
- Target gene symbol (double-evidenced CRMs): NCAM2
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 6
- Number of somatic mutations (non-coding): 0
- Related genes and loops