- Basic information
- CohesinDB ID: CDBP00414495
- Locus: chr21-21056251-21057044
-
Data sourse: GSE62063, GSE120943, GSE98367
-
Cell type: Monocytes, Macrophage, Ramos
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: NIPBL,SMC1
-
CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
27% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
-
Chromatin annotation:
"15_Quies": 79%,
"7_Enh": 7%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: PGR, NANOG, POU2F2, AGO1, POU5F1, FOXA2, TOP2A, SOX2, TEAD4, XBP1, FOXA1, CBX8, MEF2C, HOXB13, ERG, ZNF19, RELA, CREBBP, ZNF384, NEUROD1, ONECUT1, RUNX2, CHD7, ISL1, GRHL3, HIF1A, ARNT, OTX2, GATA3, NKX2-1, STAT3, PAX5, CDK8, IKZF1, SFPQ, TLE3, KMT2A, PIAS1, ESR1, SETDB1, TRPS1, PHOX2B, CTCF, NUP98-HOXA9, SPI1, EP300, BAF155, HNF4A, AR, PAX8, GATA2, ARID1A, ZNF182, EGLN2, FLI1, HSF1, RNF2, BRD4, JUND, FOXP1, CLOCK, ZIM3, NCOR2, MLLT1
- Target gene symbol (double-evidenced CRMs): NCAM2
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 15
- Number of somatic mutations (non-coding): 0
- Related genes and loops