- Basic information
- CohesinDB ID: CDBP00414496
- Locus: chr21-21061987-21065549
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Data sourse: GSE206145-GSE177045, GSE72082, GSE76893, ENCSR703TNG, GSE25021
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Cell type: MCF-7
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 4% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.989
- Subunit: NIPBL,SA1,Rad21,SMC1,Mau2
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
27% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 85%,
"5_TxWk": 6%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: PGR, SMC1A, CBX1, TOP2A, SIN3A, CTBP1, SMAD3, FOXA1, HOXB13, ERG, CREBBP, MEN1, AHR, MYC, RUNX2, GR, RAD21, ARNT, HIF1A, GATA3, GABPA, STAT3, SMARCE1, NRIP1, ZNF143, NKX3-1, CDK8, HDAC3, MED1, TLE3, NR3C1, ESRRA, NCOA3, TEAD1, ELF1, ETV1, PIAS1, NR2F1, KDM5B, ZNF217, ESR1, TCF7L2, TP73, LMO2, GRHL2, TRPS1, TCF12, EP300, BAF155, NIPBL, HNF4A, AR, TFAP2A, DPF2, ZBTB40, GATA2, ZNF479, ZBTB7A, EGLN2, FLI1, ASH2L, JUND, BRD4, CTBP2, FOXP1, CUX1, MBD2, NCOA2, STAG1, TFAP2C
- Target gene symbol (double-evidenced CRMs): NCAM2
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 49
- Number of somatic mutations (non-coding): 0
- Related genes and loops