Deatailed information for cohesin site CDBP00414500


Check detailed explainations here

  • Basic information
  • CohesinDB ID: CDBP00414500
  • Locus: chr21-21077472-21078066
  • Data sourse: GSE62063, GSE206145-GSE177045
  • Cell type: MCF-7, Ramos
  • DNA Sequence of binding site: UCSC hg38
  • Cohesin category
  • Peak occupancy ratio: 1% samples have this site.
  • Cell specificity (0: conserved, 1: cell type specific): 0.978
  • Subunit: NIPBL,Mau2
  • CTCF binding site: non-CTCF CTCF motif: False
  • Genomic location: Intragenic
  • 3D genome
  • TAD boundary: Boundary
  • Chromatin hubs: Hub
  • Hi-C loops: False Hi-ChIP loops: False ChIA-PET loops: True
  • Compartment: 27% Hi-C samples shows Compartment A
  • Cis-regulatory elements
  • Enhancer (Fantom5): non-Enhancer
  • Super enhancer (SEdb): True
  • Chromatin annotation: "15_Quies": 85%, "5_TxWk": 6%,
    Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
  • Co-bound Transcriptional factors: MAFG, CEBPA, TOP2A, SOX2, MAFF, FOXA1, HOXB13, ERG, BRG1, TOP1, RAD21, ARNT, HIF1A, OTX2, BATF3, GABPA, TAL1, NRIP1, ZNF10, CDK8, VDR, TLE3, NR3C1, CEBPB, JMJD1C, TEAD1, KMT2A, PIAS1, ESR1, C11orf30, PHOX2B, NUP98-HOXA9, MAFK, SPI1, BCL11A, BAF155, AR, GATA2, ARID1A, EGLN2, RBM25, NCOR1, BRD4, FOXP1, MLLT1, ZNF316
  • Target gene symbol (double-evidenced CRMs): NCAM2
  • Function elements
  • Human SNPs: .
  • Number of somatic mutations (coding): 3
  • Number of somatic mutations (non-coding): 0
  • Related genes and loops

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