- Basic information
- CohesinDB ID: CDBP00414504
- Locus: chr21-21096695-21097509
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Data sourse: GSE25021, GSE72082, ShirahigeLab-GSE177045
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Cell type: MCF-7
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.989
- Subunit: Mau2,SA1,Rad21
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: False
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
27% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 82%,
"1_TssA": 6%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: PGR, CBX1, ZNF316, FOXA2, MYCN, MAFG, SIN3A, CTBP1, MAFF, FOXA1, PBX2, HOXB13, ERG, AHR, RFX1, PRDM1, ARNT, PBX4, HIF1A, GRHL3, GATA3, DPF1, NFYA, FOXM1, MAX, FOS, CDK8, MITF, GATA1, TLE3, NR3C1, TEAD1, DIDO1, CREB1, PIAS1, MLLT1, ZNF217, ESR1, PKNOX1, C11orf30, L3MBTL2, GRHL2, USF1, BAF155, EP300, BCL11A, MNT, AR, BHLHE40, MAFK, GATA2, ZBTB7A, RFX5, SOX6, RAD51, BRD4, CLOCK, CUX1, NFYB, ZNF24, STAG1, RBPJ
- Target gene symbol (double-evidenced CRMs): NCAM2
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 9
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000154654,
- Related loop:
chr21:20997997-21000834~~chr21:21101368-21102780,
chr21:20998668-21000692~~chr21:21101352-21103020,
chr21:20999019-21000705~~chr21:21101429-21102752,
chr21:20999047-21000467~~chr21:21101340-21102966,
chr21:20999048-21000699~~chr21:21101364-21102683,
chr21:20999061-21000675~~chr21:21101139-21102794,
chr21:21000000-21025000~~chr21:21100000-21125000,
chr21:21003038-21004640~~chr21:21101289-21102786,
chr21:21003051-21004829~~chr21:21101340-21102914,
chr21:21003089-21004639~~chr21:21101203-21103013,
chr21:21003101-21004721~~chr21:21101174-21102946,
chr21:21003242-21004641~~chr21:21101303-21102752,
chr21:21003266-21004597~~chr21:21101164-21102785,
chr21:21003271-21004562~~chr21:21101398-21102732,
chr21:21003276-21004585~~chr21:21101357-21102787,