- Basic information
- CohesinDB ID: CDBP00414506
- Locus: chr21-21101078-21103497
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Data sourse: ENCSR000BLD, GSE206145-GSE177045, ENCSR230ZWH, ENCSR000FAD, GSE72082, GSE126634, GSE116868, ENCSR000EGW, ENCSR000BLY, GSE105028, GSE103477, GSE111537, GSE25021, GSE108869, ENCSR000EDW, ENCSR917QNE, ENCSR000EFJ, ENCSR000BTU, GSE115602, ENCSR000EAC, GSE143937, GSE165895, ENCSR000BKV, GSE115250, GSE138405, GSE93080, GSE36578, GSE76893, GSE101921, GSE152721, GSE51234, GSE120943, ENCSR198ZYJ, GSE206145-NatGen2015, GSE112028, GSE130135, ENCSR703TNG, GSE106870, GSE116344, GSE138105, GSE145327, GSE94872, ENCSR000EEG, GSE76815, GSE98367, ENCSR879KXD, ENCSR000BLS, ENCSR000EHW, GSE206145, ENCSR000ECE, GSE62063, ENCSR000EHX, GSE97394, GSE55407, ENCSR000BTQ, GSE105004, ENCSR167MTG, GSE129526, ENCSR000HPG, GSE38411, ENCSR000EDE, ENCSR153HNT, GSE68388, GSE126990, GSE50893, ENCSR000ECS, GSE131577
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Cell type: MDM, RH4, GM2610, SLK, CVB-hiPSC, CVI-hiPSC, Liver, GP5d, TC-32, HuCC-T1, H9-hESC, GM2630, Fibroblast, THP-1, Ishikawa, HeLa-S3, GM2255, IMR-90, BCBL-1, K-562, GM18486, HFFc6, GM18526, H1-hESC, SNYDER, Monocytes, GM18505, MB157, GM12878, GM12891, GM2588, HUES9, SK-N-SH, GM19239, HeLa-Tet-On, HAP1, GM19099, HUES64, Macrophage, MCF-7, Ramos, Hela-Kyoto, HCT-116, HL-60, HEK293T, Hep-G2, MCF-10A, Neurons-H1, HUVEC, GM19238, HeLa, BGO3, OCI-AML-3, GM18951
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 36% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.389
- Subunit: NIPBL,SA1,Rad21,SMC1,SMC3ac,SA2,Mau2,SMC3
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CTCF binding site: CTCF
CTCF motif: True
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
27% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 69%,
"7_Enh": 14%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: AR, SOX2, XBP1, HIF1A, BRD4, FOXA1, SETDB1, CDK8
- Target gene symbol (double-evidenced CRMs): NCAM2
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 34
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000154654,
- Related loop:
chr21:20997997-21000834~~chr21:21101368-21102780,
chr21:20998668-21000692~~chr21:21101352-21103020,
chr21:20999019-21000705~~chr21:21101429-21102752,
chr21:20999047-21000467~~chr21:21101340-21102966,
chr21:20999048-21000699~~chr21:21101364-21102683,
chr21:20999061-21000675~~chr21:21101139-21102794,
chr21:21000000-21025000~~chr21:21100000-21125000,
chr21:21003038-21004640~~chr21:21101289-21102786,
chr21:21003051-21004829~~chr21:21101340-21102914,
chr21:21003089-21004639~~chr21:21101203-21103013,
chr21:21003101-21004721~~chr21:21101174-21102946,
chr21:21003242-21004641~~chr21:21101303-21102752,
chr21:21003266-21004597~~chr21:21101164-21102785,
chr21:21003271-21004562~~chr21:21101398-21102732,
chr21:21003276-21004585~~chr21:21101357-21102787,