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Basic information

CohesinDB ID: CDBP00414520

Locus: chr21-21176166-21176643

Data sourse: GSE62063

Cell type: Ramos

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 0% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.989

Subunit: NIPBL

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: False

Compartment: 27% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 74%, "1_TssA": 9%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: MEIS2, FOXA1, PBX2, ATF3, CHD7, PRDM1, SMARCE1, ETV1, CTCF, TCF12, DPF2, IRF4, TEAD4, MTA2, NBN, ARID3A, TBP, ERG, OGG1, SMARCC2, MYC, SMARCA4, RFX1, ARID1B, GRHL3, RCOR1, NR2F6, NR3C1, CEBPB, STAT5B, SPI1, IRF1, GATA2, ZSCAN29, SMARCA5, CC2D1A, RUNX1, HDAC1, SIN3A, ZFX, CREBBP, RUNX2, PBX4, ZEB2, HMBOX1, PBX3, CBFA2T3, FOS, CDK8, SMARCB1, CEBPD, MYB, GTF3C2, SETDB1, EVI1, MAFK, USF1, NR4A1, MLLT1, STAG1, EBF1, WT1, FOXF1, ZBTB33, ZNF823, CDK9, HOXB13, RELA, CHAMP1, ISL1, GATA3, TAL1, GATA1, HAND2, ZNF592, NR2F2, NR2F1, TCF7L2, PKNOX1, PHOX2B, T, ELF3, ZBTB40, NCOR1, BRD4, JUND, ZNF24, ADNP

Target gene symbol (double-evidenced CRMs): NCAM2

Function elements

Human SNPs: .

Number of somatic mutations (coding): 2

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000154654,

eachgene

Deatailed information for cohesin site CDBP00414520