- Basic information
- CohesinDB ID: CDBP00414524
- Locus: chr21-21193044-21193804
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Data sourse: GSE67783, GSE86191, GSE206145-NatGen2015, GSE62063, GSE103477
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Cell type: MDM, Fibroblast, HCT-116, HSPC, Ramos
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.944
- Subunit: NIPBL,SA1,Rad21
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
27% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 87%,
"5_TxWk": 7%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, PGR, FOXA2, POU5F1, MTA3, HDAC1, SOX2, NME2, CTBP1, MTA2, MEIS2, MAFF, TEAD4, STAT1, FOXA1, ZBTB33, ZNF823, NBN, PBX2, HOXB13, ERG, RELA, HDGF, CREBBP, ZNF384, OGG1, NFKB2, ATF3, EHMT2, SMARCA4, ARID1B, RAD21, ARNT, NKX2-1, ATF2, GATA3, ZEB2, STAT3, NRIP1, GATA1, IKZF1, CDK8, FOS, HAND2, DACH1, NFE2, TLE3, NR3C1, CEBPB, ZNF592, NCOA3, ETV1, PIAS1, NR2F1, TCF7L2, ESR1, PKNOX1, NFKB1, SETDB1, JUN, SPI1, BAF155, E4F1, AR, IRF1, DPF2, ZBTB40, GATA2, HDAC2, SOX6, FLI1, NCOR1, JUND, SMARCA5, BRD4, NCOA2, STAT2, MLLT1, AHR
- Target gene symbol (double-evidenced CRMs): NCAM2
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 9
- Number of somatic mutations (non-coding): 0
- Related genes and loops