Deatailed information for cohesin site CDBP00414528

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  • Basic information
  • CohesinDB ID: CDBP00414528
  • Locus: chr21-21199016-21199562
  • Data sourse: GSE206145-NatGen2015
  • Cell type: Fibroblast
  • DNA Sequence of binding site: UCSC hg38
  • Cohesin category
  • Peak occupancy ratio: 0% samples have this site.
  • Cell specificity (0: conserved, 1: cell type specific): 0.989
  • Subunit: Mau2
  • CTCF binding site: non-CTCF CTCF motif: False
  • Genomic location: Intragenic
  • 3D genome
  • TAD boundary: Boundary
  • Chromatin hubs: Hub
  • Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True
  • Compartment: 27% Hi-C samples shows Compartment A
  • Cis-regulatory elements
  • Enhancer (Fantom5): non-Enhancer
  • Super enhancer (SEdb): True
  • Chromatin annotation: "15_Quies": 72%, "7_Enh": 18%,
    Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
  • Co-bound Transcriptional factors: FOXO1, FOSL1, PGR, SMARCA2, E2F7, SOX2, MEIS2, NME2, XBP1, FOXA1, RBFOX2, PBX2, HDGF, ATF3, NFIC, CHD7, ATF4, SMARCE1, TP63, MITF, MAF, ELF1, TEAD1, TRIM28, KLF6, ETV1, NFE2L2, SMAD5, ESR1, HNF1B, TP73, MLL, JUN, TCF12, EP300, E4F1, KLF1, MNT, DPF2, SOX4, E2F6, TRIM24, IRF4, SOX6, CREB3, RAD51, DDX20, E2F1, TEAD4, ZNF175, EHMT2, CHD8, POU5F1, TOP2A, ID3, RUNX1T1, CTBP1, MTA2, STAT1, SRF, NBN, ARID3A, TBP, ERG, PAX6, HOXC5, SMARCC2, MYC, SMARCA4, ARID1B, RAD21, FOXP2, GRHL3, RXRA, NKX2-1, FOXK2, GABPA, STAT3, XRCC5, IKZF1, RCOR1, LEF1, NR2F6, NFRKB, DACH1, VDR, NR3C1, CEBPB, ESRRA, NFE2, STAT5B, TBL1XR1, EBF3, ELF4, ZHX2, SPI1, EHF, IRF1, HDAC2, GATA2, GATAD2B, TAF9B, FLI1, NR2C2, ZNF766, MRTFB, NCOA2, EP400, ZIM3, ATF1, CC2D1A, RUNX1, MAFG, HDAC1, SIN3A, ZFX, AFF4, SMAD3, SMARCC1, NSD2, MEF2A, IRF2, ZBTB2, ZNF384, BRD9, RUNX2, CDK6, ARNT, BACH1, PBX4, DAXX, ATF2, HMBOX1, ZEB2, PBX3, CBFA2T3, NR2C1, SUPT5H, CDK8, FOXM1, FOS, MED1, ZNF584, GMEB1, PML, SPDEF, MYB, PIAS1, C11orf30, L3MBTL2, NCOA1, SETDB1, EVI1, STAT5A, USF1, BCL11A, SP1, MAFK, NR4A1, REST, ZBTB7A, ATF7, AFF1, MBD2, FOXP1, STAT2, MLLT1, PTTG1, NFATC3, PPARG, FOXA2, MTA3, RBBP5, CBX3, CREM, E2F8, MAFF, FOXF1, ZBTB33, HOXB13, ZNF318, ZNF589, CREB3L1, RELA, YY1, KDM1A, JUNB, NEUROD1, CHAMP1, HIF1A, GATA3, MGA, TAL1, MAX, ZNF143, GATA1, MTA1, CEBPG, ZNF592, KLF4, NCOA3, NR2F2, NR2F1, TP53, PKNOX1, NFKB1, BRD2, ELF3, TBX21, BHLHE40, AR, PTRF, TAF1, ZBTB40, YAP1, EGLN2, HSF1, RNF2, NOTCH3, JUND, BRD4, NCOR1, ILF3, ZNF24, ZNF316, FOSL2
  • Target gene symbol (double-evidenced CRMs): NCAM2
  • Function elements
  • Human SNPs: .
  • Number of somatic mutations (coding): 6
  • Number of somatic mutations (non-coding): 0
  • Related genes and loops
  • Related gene: ENSG00000154654,
  • Related loop: chr21:18275000-18300000~~chr21:21200000-21225000, chr21:21000000-21025000~~chr21:21200000-21225000, chr21:21175000-21200000~~chr21:21600000-21625000, chr21:21175000-21200000~~chr21:21675000-21700000, chr21:21175000-21200000~~chr21:21700000-21725000, chr21:21175000-21200000~~chr21:21900000-21925000, chr21:21175000-21200000~~chr21:25325000-25350000, chr21:21175000-21200000~~chr21:25350000-25375000, chr21:21200000-21225000~~chr21:21900000-21925000,
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