Browse_each

Basic information

CohesinDB ID: CDBP00414534

Locus: chr21-21230579-21234343

Data sourse: ENCSR000BLD, GSE206145-GSE177045, ENCSR230ZWH, ENCSR000FAD, GSE72082, GSE126634, GSE116868, GSE132649, ENCSR000BLY, ENCSR404BPV, GSE105028, GSE103477, GSE111537, GSE25021, GSE108869, ENCSR917QNE, ENCSR000EFJ, ENCSR000BTU, GSE115602, ENCSR000DZP, ENCSR000EAC, GSE139435, ENCSR000BKV, GSE115250, GSE138405, GSE143937, GSE76893, GSE101921, GSE135093, GSE152721, GSE206145-NatGen2015, ENCSR198ZYJ, GSE112028, GSE130135, ENCSR703TNG, GSE138105, GSE145327, GSE94872, ENCSR000EEG, GSE76815, GSE115248, ENCSR879KXD, ENCSR000BLS, ENCSR000EHW, GSE206145, ENCSR000ECE, GSE62063, ENCSR000BMY, ENCSR000EHX, ENCSR635OSG, ENCSR495WGO, GSE97394, GSE55407, ENCSR000BTQ, GSE105004, ENCSR167MTG, ENCSR956LGB, GSE129526, ENCSR000HPG, ENCSR000EDE, GSE68388, GSE126990, GSE50893, ENCSR000ECS, GSE131577

Cell type: MDM, GM2610, SLK, Liver, TC-32, HuCC-T1, H9-hESC, RPE, GM2630, Fibroblast, Ishikawa, Kelly, HeLa-S3, IMR-90, K-562, GM18486, GM18526, H1-hESC, SNYDER, Leukemia-SEM, MB157, GM12878, GM12891, GM2588, SK-N-SH, GM19239, HeLa-Tet-On, THP-1, HUES64, MCF-7, Ramos, T-47D, Hela-Kyoto, HCT-116, HL-60, HEK293T, Hep-G2, MCF-10A, Neurons-H1, A-549, HUVEC, HCAEC, GM19238, HeLa, CNCC-WT33iPSC, OCI-AML-3, HAP1

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 39% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.467

Subunit: NIPBL,SA1,Rad21,SMC1,SMC3ac,SA2,Mau2,SMC3

CTCF binding site: CTCF CTCF motif: True

Genomic location: TSS,Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 27% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 82%, "7_Enh": 8%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: MIER1, REST, ONECUT1, IRF4, PIAS1, ARNT, HIF1A, DUX4, GABPA, STAT3, TEAD4, HOXB13, BAF155, EHMT2, ERG

Target gene symbol (double-evidenced CRMs): NCAM2

Function elements

Human SNPs: .

Number of somatic mutations (coding): 55

Number of somatic mutations (non-coding): 19

Related genes and loops

Related gene: ENSG00000154654,

eachgene

Deatailed information for cohesin site CDBP00414534