- Basic information
- CohesinDB ID: CDBP00414544
- Locus: chr21-21267722-21270230
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Data sourse: GSE206145-GSE177045, GSE72082, GSE138405, GSE25021, GSE62063, ENCSR703TNG, GSE126990
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Cell type: MCF-7, Hela-Kyoto, Ramos
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 3% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: NIPBL,SA1,Rad21,SA2,Mau2
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
24% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 82%,
"7_Enh": 9%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: PGR, SMC1A, POU2F2, CHD8, POU5F1, FOXA2, TOP2A, SIN3A, NME2, XBP1, FOXA1, HOXB13, HNF4G, ERG, ZNF300, RELA, CREBBP, HOXC5, MEN1, ASCL1, RUNX2, MYC, BRG1, RFX1, GR, RAD21, PRDM1, ARNT, HIF1A, GRHL3, PBX4, NKX2-1, GATA3, ISL1, GABPA, OTX2, PAX5, ETV6, NKX3-1, NRIP1, MED1, TLE3, NR3C1, CEBPB, TEAD1, TFAP2C, PIAS1, ESR1, GRHL2, TRPS1, PHOX2B, JUN, TCF12, CTCF, BAF155, EP300, TFAP2A, NUP98-HOXA9, AR, MNT, GATA2, ARID1A, BRD4, JUND, MBD2, CUX1, TEAD4, NCOR2, STAG1, AHR
- Target gene symbol (double-evidenced CRMs): NCAM2
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 25
- Number of somatic mutations (non-coding): 0
- Related genes and loops