- Basic information
- CohesinDB ID: CDBP00414551
- Locus: chr21-21283545-21284157
-
Data sourse: GSE62063, ShirahigeLab-GSE177045
-
Cell type: MCF-7, Ramos
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: NIPBL,Mau2
-
CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: False
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
24% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
-
Chromatin annotation:
"15_Quies": 91%,
"9_Het": 4%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: RUNX1, PGR, FOXA2, FOXA1, HOXB13, ERG, YY1, ISL1, TOP1, ARNT, RXRA, GATA3, PAX5, NKX3-1, CHD1, HAND2, TLE3, CEBPB, PIAS1, EZH2, ESR1, ZNF334, EBF3, PHOX2B, EP300, BAF155, HNF4A, AR, GATA2, MAML3, BRD4, TEAD4
- Target gene symbol (double-evidenced CRMs): NCAM2
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 8
- Number of somatic mutations (non-coding): 0
- Related genes and loops