- Basic information
- CohesinDB ID: CDBP00414555
- Locus: chr21-21292007-21292528
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Data sourse: ENCSR000EHW, GSE206145-GSE177045, ENCSR000EHX, ENCSR000BLY
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Cell type: MCF-7, SK-N-SH
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: Mau2,SMC3,Rad21
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: False
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
24% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 87%,
"5_TxWk": 9%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: MYCN, CHD2, TWIST1, ERG, ZNF19, ISL1, RAD21, ARNT, GATA3, STAT3, RCOR1, HAND2, LMO2, ESR1, PITX3, EBF3, PHOX2B, RBM22, TCF12, EP300, BAF155, AR, GATA2, IRF4, MAML3, BRD4, TEAD4, TBX2
- Target gene symbol (double-evidenced CRMs): NCAM2
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 168
- Number of somatic mutations (non-coding): 31
- Related genes and loops