- Basic information
- CohesinDB ID: CDBP00414557
- Locus: chr21-21296881-21297766
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Data sourse: GSE206145-GSE177045
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Cell type: MCF-7
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.989
- Subunit: Mau2,Rad21
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: False
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
24% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 88%,
"5_TxWk": 9%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, NANOG, FOXA2, POU5F1, TOP2A, NME2, DUX4, FOXA1, HOXB13, ERG, RELA, CREBBP, ONECUT1, GATA4, ISL1, TOP1, ARNT, HIF1A, GATA3, GABPA, STAT3, NKX3-1, SUPT5H, GATA1, DACH1, MED1, VDR, CSNK2A1, TLE3, GMEB1, CEBPB, ETV1, PIAS1, CREB1, ESR1, PHOX2B, RBM22, BAF155, EP300, AR, GATA2, ARID1A, BRD4, FOXP1, CLOCK, TEAD4, AHR
- Target gene symbol (double-evidenced CRMs): NCAM2
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 20
- Number of somatic mutations (non-coding): 3
- Related genes and loops