Deatailed information for cohesin site CDBP00414567


Check detailed explainations here

  • Basic information
  • CohesinDB ID: CDBP00414567
  • Locus: chr21-21335462-21336404
  • Data sourse: ENCSR703TNG, GSE206145-GSE177045, GSE76893
  • Cell type: MCF-7
  • DNA Sequence of binding site: UCSC hg38
  • Cohesin category
  • Peak occupancy ratio: 2% samples have this site.
  • Cell specificity (0: conserved, 1: cell type specific): 0.989
  • Subunit: NIPBL,Rad21,Mau2
  • CTCF binding site: non-CTCF CTCF motif: False
  • Genomic location: Intragenic
  • 3D genome
  • TAD boundary: Boundary
  • Chromatin hubs: Hub
  • Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True
  • Compartment: 24% Hi-C samples shows Compartment A
  • Cis-regulatory elements
  • Enhancer (Fantom5): non-Enhancer
  • Super enhancer (SEdb): True
  • Chromatin annotation: "15_Quies": 92%, "5_TxWk": 6%,
    Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
  • Co-bound Transcriptional factors: PGR, SIN3A, FOXA1, HOXB13, ERG, HNRNPK, RELA, CREBBP, MEN1, GATA3, ATF2, NKX3-1, MED1, VDR, TLE3, NR3C1, ESRRA, TEAD1, NR2F2, CREB1, NR2F1, PIAS1, ETV1, ESR1, ZHX2, TCF12, NIPBL, SPI1, BAF155, EP300, AR, GATA2, ARID1A, BRD4, JUND
  • Target gene symbol (double-evidenced CRMs): NCAM2
  • Function elements
  • Human SNPs: .
  • Number of somatic mutations (coding): 124
  • Number of somatic mutations (non-coding): 0
  • Related genes and loops

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