- Basic information
- CohesinDB ID: CDBP00414575
- Locus: chr21-21357570-21358689
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Data sourse: GSE62063, GSE76893, GSE206145-GSE177045
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Cell type: MCF-7, Ramos
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: NIPBL,Mau2
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
24% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 95%,
"9_Het": 4%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, ZNF394, ZNF283, ZNF426, PGR, NANOG, ZNF697, ZNF316, FOXA2, TOP2A, SIN3A, GTF2B, MAFF, FOXA1, ZBTB33, HOXB13, HNF4G, ERG, RELA, CREBBP, ZXDC, MEN1, AHR, ONECUT1, MYC, ZFP64, BRG1, ARNT, HIF1A, PRDM12, GATA3, ZNF518A, FOXM1, NKX3-1, CHD1, ZNF143, MED1, VDR, TLE3, NR3C1, ESRRA, CSNK2A1, TEAD1, CREB1, PIAS1, ESR1, TCF12, MAFK, BAF155, EP300, AR, DPF2, GATA2, ARID1A, YAP1, REST, BRD4, JUND, CTBP2, FOXP1, CUX1, TEAD4, ZNF34, TFAP2C
- Target gene symbol (double-evidenced CRMs): NCAM2
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 22
- Number of somatic mutations (non-coding): 0
- Related genes and loops