- Basic information
- CohesinDB ID: CDBP00414576
- Locus: chr21-21364506-21364733
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Data sourse: GSE138405, GSE62063, GSE126990
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Cell type: Hela-Kyoto, Ramos
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: NIPBL,SMC3
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
24% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 82%,
"7_Enh": 10%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOSL1, PGR, SOX2, NME2, XBP1, HNF1A, CHD7, MITF, TEAD1, ETV1, NFE2L2, ESR1, PITX3, CTCF, JUN, TCF12, EP300, SOX5, E2F6, E2F1, TEAD4, RBPJ, TFAP2C, NANOG, CHD8, POU5F1, MYCN, TOP2A, SRF, ASCL1, SMARCA4, EOMES, RAD21, LHX2, STAT3, XRCC5, SOX10, RCOR1, VDR, ARNTL, NR3C1, CEBPB, CREB1, EBF3, HDAC2, FLI1, MRTFB, CEBPA, SOX13, POU4F2, SMAD3, SMARCC1, TWIST1, RARA, CREBBP, RUNX2, PBX4, ATF2, PRDM9, FOXM1, MED1, USF1, SP1, BCL11A, REST, ASH2L, PCGF2, FOXP1, SMC3, EBF1, CHD2, ZSCAN16, GTF2B, KDM1A, YY1, RELA, NEUROD1, ISL1, HIF1A, OTX2, GATA3, MAX, HAND2, KDM5B, PHOX2B, BRD2, T, AR, TAF1, NOTCH3, BRD4, JUND, CUX1, TBX2, FOSL2
- Target gene symbol (double-evidenced CRMs): NCAM2
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 8
- Number of somatic mutations (non-coding): 0
- Related genes and loops