- Basic information
- CohesinDB ID: CDBP00414581
- Locus: chr21-21376479-21377878
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Data sourse: GSE62063, GSE206145-GSE177045
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Cell type: MCF-7, Ramos
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: NIPBL,Mau2
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
24% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 92%,
"9_Het": 4%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: AR, VDR, TLE3, NR3C1, HOXB13, GATA2, ARID1A, PGR, CREBBP, PIAS1, ESR1, SRSF9, FOXA1, GATA3, NKX3-1, CHD1, EP300, ERG
- Target gene symbol (double-evidenced CRMs): NCAM2
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 38
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000154654,
- Related loop:
chr21:20998922-21001330~~chr21:21372954-21374952,
chr21:21000000-21025000~~chr21:21350000-21375000,
chr21:21000000-21025000~~chr21:21375000-21400000,
chr21:21003128-21004732~~chr21:21372936-21375055,
chr21:21003151-21004646~~chr21:21372959-21374950,
chr21:21150000-21175000~~chr21:21350000-21375000,
chr21:21162538-21166096~~chr21:21372954-21374952,
chr21:21163052-21166114~~chr21:21372959-21374950,
chr21:21225000-21250000~~chr21:21350000-21375000,
chr21:21350000-21375000~~chr21:21600000-21625000,
chr21:21350000-21375000~~chr21:21675000-21700000,
chr21:21350000-21375000~~chr21:21900000-21925000,
chr21:21350000-21375000~~chr21:22775000-22800000,
chr21:21373026-21375271~~chr21:21920936-21923160,
chr21:21375000-21400000~~chr21:21900000-21925000,
chr21:21375000-21400000~~chr21:22775000-22800000,