- Basic information
- CohesinDB ID: CDBP00414643
- Locus: chr21-21612405-21613123
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Data sourse: ENCSR000BLD, ENCSR000EFJ, GSE138405, ENCSR000BLY, GSE206145-NatGen2015, ENCSR000ECE, ENCSR000EHX, GSE126990, ENCSR000ECS
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Cell type: H1-hESC, Fibroblast, Hela-Kyoto, HeLa-S3, IMR-90, SK-N-SH
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 4% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.933
- Subunit: SA1,Rad21,SA2,Mau2,SMC3
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: TES
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
24% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 79%,
"7_Enh": 12%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOXO1, FOSL1, PGR, CHD8, PPARG, NANOG, MYCN, TEAD4, SMAD3, FOXA1, SRF, TWIST1, HOXC5, RELA, JUNB, NFIC, SMARCA4, RAD21, CHD7, PBX4, HIF1A, LHX2, OTX2, GATA3, GABPA, STAT3, MAX, PBX3, FOS, RCOR1, MED1, NR3C1, CEBPB, TEAD1, MLL, PKNOX1, NFKB1, BRD2, TCF12, CTCF, SP1, SPI1, EP300, JUN, AR, TAF1, GATA2, REST, FLI1, BRD4, JUND, FOXP1, MRTFB, NCOA2, FOSL2
- Target gene symbol (double-evidenced CRMs): NCAM2
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops