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Basic information

CohesinDB ID: CDBP00414698

Locus: chr21-21896953-21898185

Data sourse: ENCSR000BTQ, GSE206145-GSE177045, GSE72082, GSE76893, ENCSR000BLY, GSE101921, GSE206145-NatGen2015, ENCSR703TNG, GSE25021, ENCSR917QNE

Cell type: MCF-7, Fibroblast, MCF-10A, SK-N-SH, Liver

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 6% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.944

Subunit: NIPBL,SA1,Rad21,SMC1,SA2,Mau2

CTCF binding site: non-CTCF CTCF motif: True

Genomic location: Intergenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: False Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 25% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 84%, "9_Het": 11%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: RELA, AR, POU2F2, PGR, GR, POU2F3, TEAD4, NOTCH3, ESR1, FOXA1, GRHL2, PHOX2B, TP63

Target gene symbol (double-evidenced CRMs): .

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 11

Related genes and loops

Related gene:

eachgene

Deatailed information for cohesin site CDBP00414698