- Basic information
- CohesinDB ID: CDBP00414715
- Locus: chr21-21997396-21997506
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Data sourse: GSE120943, GSE98367
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Cell type: Monocytes, Macrophage
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: SMC1
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
25% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 76%,
"9_Het": 21%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, CHD8, FOXA2, EBF1, RUNX1T1, KDM4C, ZFX, FOXA1, HOXB13, SMARCC1, ERG, RELA, CREBBP, PBX1, NOTCH1, ATF3, ARNT, HIF1A, ATF2, GATA3, GABPA, TAL1, MAX, ZNF143, CDK8, ARNTL, ZNF750, JMJD1C, MYB, CREB1, KDM5B, LMO2, ESR1, MED, GRHL2, PHOX2B, JUN, BRD2, SPI1, EP300, TFAP2A, LMO1, AR, HNF4A, TRIM24, EGLN2, ATF7, FLI1, HSF1, NOTCH3, JUND, BRD4, TCF3, E2F1, MRTFB, ATF1, TFAP2C
- Target gene symbol (double-evidenced CRMs): .
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 4
- Related genes and loops