- Basic information
- CohesinDB ID: CDBP00414730
- Locus: chr21-22120614-22121391
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Data sourse: ENCSR000BLD, GSE206145-GSE177045, ENCSR230ZWH, ENCSR000FAD, GSE72082, GSE126634, ENCSR000EGW, ENCSR000BLY, GSE105028, GSE103477, GSE111537, GSE25021, ENCSR917QNE, ENCSR000EFJ, ENCSR000BTU, GSE143937, GSE67783, ENCSR000BKV, GSE86191, GSE138405, GSE152721, GSE206145-NatGen2015, ENCSR703TNG, GSE106870, GSE116344, GSE145327, GSE118494, ENCSR000EEG, ENCSR000BLS, GSE85526, ENCSR000ECE, ENCSR000EHX, ENCSR635OSG, GSE97394, ENCSR000BTQ, GSE105004, GSE110061, GSE129526, ENCSR000HPG, GSE126990, GSE50893, GSE131577
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Cell type: MDM, RH4, GM2610, CVB-hiPSC, Liver, H9-hESC, GM2630, Fibroblast, HEKn, Ishikawa, IMR-90, K-562, H1-hESC, SNYDER, GM2588, SK-N-SH, GM19239, HAP1, HUES64, MCF-7, GM12892, Hela-Kyoto, HCT-116, HL-60, Hep-G2, HeLa, OCI-AML-3, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 17% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.689
- Subunit: SA1,Rad21,SMC1,SA2,SMC3
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CTCF binding site: CTCF
CTCF motif: True
- Genomic location: TES
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
22% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 67%,
"9_Het": 32%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: SMC1A, CBX1, MYCN, ZFX, DUX4, ZBTB48, SRF, ZBTB33, ARID3A, YY1, RELA, CTCFL, CHD7, SP140, RAD21, NKX2-1, MAX, XRCC5, ZNF143, IKZF1, DACH1, ARNTL, ZNF506, ESR1, SETDB1, KLF16, CTCF, MAFK, AR, RYBP, RB1, NOTCH3, MAZ, SMC3
- Target gene symbol (double-evidenced CRMs): NCAM2
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 7
- Related genes and loops
- Related gene:
ENSG00000154654,
- Related loop:
chr21:20975000-21000000~~chr21:22100000-22125000,
chr21:21000000-21025000~~chr21:22100000-22125000,
chr21:21225000-21250000~~chr21:22100000-22125000,
chr21:21675000-21700000~~chr21:22100000-22125000,
chr21:21700000-21725000~~chr21:22100000-22125000,
chr21:21900000-21925000~~chr21:22100000-22125000,
chr21:21925000-21950000~~chr21:22100000-22125000,
chr21:22100000-22125000~~chr21:22550000-22575000,
chr21:22100000-22125000~~chr21:22775000-22800000,