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Basic information

CohesinDB ID: CDBP00414745

Locus: chr21-22189711-22191053

Data sourse: GSE138405, GSE126990, GSE67783, ENCSR879KXD

Cell type: K-562, Hela-Kyoto, HSPC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.967

Subunit: SA1,Rad21,SA2

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intergenic

3D genome

TAD boundary: non-Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 22% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 91%, "9_Het": 8%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: ZNF394, HDAC1, CBX3, ZNF660, TOP2A, ID3, TEAD4, ZBTB48, FOXA1, NBN, RBFOX2, PRDM10, HDGF, ZNF384, NEUROD1, ATF3, BRD9, SMARCA4, ARID1B, ATF4, OTX2, FOXK2, GATA3, ZEB2, GABPA, SMARCE1, MAX, GATA1, SUPT5H, NR2F6, NFRKB, DACH1, CEBPG, CEBPB, TEAD1, NR2F2, PML, ELF1, NR2F1, ZMYM3, KDM5B, SMAD5, TP53, ESR1, GABPB1, PHF8, E4F1, MNT, TAF1, DPF2, ZBTB40, HDAC2, ZNF479, TAF9B, RNF2, HNRNPLL, BRD4, ILF3, E2F1, EP400, SMC3, ATF1, MLLT1, RBPJ

Target gene symbol (double-evidenced CRMs): .

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 13

Related genes and loops

Related gene:

eachgene

Deatailed information for cohesin site CDBP00414745