- Basic information
- CohesinDB ID: CDBP00414805
- Locus: chr21-22420818-22421243
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Data sourse: GSE120943, GSE67783, GSE86191
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Cell type: Monocytes, HCT-116, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: SA1,Rad21,SMC1
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: TES
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: False
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
23% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 79%,
"7_Enh": 10%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, FOXO1, ZNF283, CEBPA, CDK7, RUNX1T1, GTF2B, ZBTB48, DUX4, STAT1, FOXA1, ZBTB33, CDK9, HOXB13, SMARCC1, ERG, KDM1A, RELA, NOTCH1, LYL1, MYC, RFX1, PRDM1, ARNT, PROX1, GATA3, GABPA, MECOM, TAL1, ZEB2, SUPT5H, CDK8, MED1, BCL11B, JMJD1C, TRIM28, MYB, KMT2A, TCF7L2, LMO2, MLL, ZNF334, EVI1, STAT5A, ELF3, TCF12, SPI1, ARID5B, BCL11A, LMO1, PAX3-FOXO1, NR4A1, GATA2, TRIM24, FLI1, BRD4, TCF3, TEAD4, KMT2B, STAG1, RBPJ
- Target gene symbol (double-evidenced CRMs): .
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 9
- Related genes and loops