- Basic information
- CohesinDB ID: CDBP00414824
- Locus: chr21-22535178-22537033
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Data sourse: ENCSR000BLD, GSE67783, GSE86191, GSE138405, GSE25021, GSE76893, GSE105028, ENCSR000EDE, GSE126990, GSE108869, ENCSR000ECS
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Cell type: MCF-7, H1-hESC, Hela-Kyoto, HCT-116, HeLa-S3, HSPC, H9-hESC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 3% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.922
- Subunit: NIPBL,SA1,Rad21,SA2,SMC3
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
25% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 68%,
"9_Het": 30%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOSL1, PGR, XBP1, SNAPC4, FOXA1, ATF3, CHD7, SMARCE1, JMJD1C, MAF, TRIM28, NFE2L2, ESR1, OCA2, CTCF, JUN, TCF12, EP300, BAF155, DPF2, TRIM24, RFX5, ZNF92, CHD8, ZSCAN5D, MYCN, CTBP1, ZBTB48, DUX4, TBP, HOXC5, ERG, MYC, RAD21, LHX2, GRHL3, NKX2-1, GABPA, STAT3, UBN1, RCOR1, NFE2, VDR, NR3C1, CEBPB, ESRRA, CREB1, EZH2, NFE2L1, SPI1, GATA2, GATAD2B, FLI1, MRTFB, NCOA2, MAFG, CBX1, SIN3A, ZFX, SMAD3, CREBBP, ARNT, PBX4, DAXX, BACH1, NRF1, ATF2, FOXM1, FOS, CDK8, PIAS1, C11orf30, MAFK, NIPBL, BCL11A, ATF7, HNRNPLL, CTBP2, SMC3, MLLT1, STAG1, FOXA2, MAFF, ESR2, RELA, JUNB, AHR, HIF1A, OTX2, GATA3, MAX, NRIP1, ZNF143, MTA1, GATA1, NCOA3, NR2F2, NR2F1, TP53, NFKB1, AR, EGLN2, EGR1, NCOR1, NOTCH3, BRD4, JUND, IRF9, ZNF316, FOSL2
- Target gene symbol (double-evidenced CRMs): NCAM2
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 24
- Related genes and loops