- Basic information
- CohesinDB ID: CDBP00414887
- Locus: chr21-22789800-22793340
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Data sourse: ENCSR230ZWH, ENCSR000FAD, ENCSR000BSB, ENCSR000EGW, GSE131606, ENCSR330ELC, ENCSR000BUC, ENCSR917QNE, GSE139435, GSE93080, GSE101921, ENCSR806UKK, GSE51234, GSE120943, ENCSR198ZYJ, GSE112028, GSE130135, ENCSR199XBQ, GSE94872, ENCSR895JMI, ENCSR000EEG, GSE130140, GSE115248, ENCSR247LSH, GSE105004, ENCSR676MJK, GSE155324, ENCSR054FKH, GSE126755, ENCSR748MVX, ENCSR000ECS, GSE131577, ENCSR000BLD, GSE104888, GSE126634, GSE103477, GSE108869, GSE143937, GSE138405, GSE135093, ENCSR193NSH, GSE206145, GSE85526, ENCSR000ECE, ENCSR620NWG, ENCSR767DFK, ENCSR984DZW, ENCSR000BTQ, GSE129526, ENCSR760NPX, ENCSR000BLY, ENCSR150EFU, GSE121355, GSE111537, GSE25021, ENCSR000EAC, GSE122299, GSE115250, GSE76893, GSE145327, ENCSR000BMY, ENCSR000EHX, GSE97394, ENCSR217ELF, GSE131956, GSE110061, ENCSR000HPG, ENCSR335RKQ, ENCSR000EDE, GSE50893, GSE206145-GSE177045, GSE72082, ENCSR501LQA, ENCSR404BPV, GSE105028, ENCSR000EDW, ENCSR000EFJ, ENCSR000BTU, ENCSR000DZP, ENCSR000BKV, GSE152721, GSE206145-NatGen2015, GSE138105, ENCSR703TNG, GSE98367, ENCSR768DOX, ENCSR879KXD, ENCSR000BLS, ENCSR000EHW, ENCSR981FDC, ENCSR807WAC, GSE62063, ENCSR495WGO, ENCSR167MTG, ENCSR853VWZ, ENCSR956LGB, ENCSR944ZCT, GSE68388, GSE126990
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Cell type: MDM, GM10847, GM2610, SLK, GM19240, OCI-AML-3, CUTLL1, Liver, GP5d, TC-32, HuCC-T1, B-cell, H9-hESC, GM2630, HMEC, Fibroblast, RPE, HEKn, THP-1, Ishikawa, Kelly, GM12890, HeLa-S3, GM2255, IMR-90, K-562, GM18486, DKO, GM18526, H1-hESC, SNYDER, Monocytes, GM18505, Leukemia-SEM, Lymphoblast, GM12878, GM12891, GM2588, GBM39, SK-N-SH, GM19239, HeLa-Tet-On, GM19193, HAP1, GM19099, HUES64, Macrophage, GM12892, MCF-7, Hela-Kyoto, HCT-116, HL-60, HEK293T, Hep-G2, MCF-10A, Neurons-H1, A-549, HUVEC, HCAEC, Ramos, GM19238, HeLa, CNCC-WT33iPSC, TC-71, Neutrophil, GM18951
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 60% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.256
- Subunit: NIPBL,SA1,Rad21,SMC1,SMC3ac,SA2,SMC3
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CTCF binding site: CTCF
CTCF motif: True
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
25% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 95%,
"9_Het": 2%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: AHR, ARNT
- Target gene symbol (double-evidenced CRMs): NCAM2
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 35
- Related genes and loops
- Related gene:
ENSG00000154654,
- Related loop:
chr21:18275000-18300000~~chr21:22775000-22800000,
chr21:18300000-18325000~~chr21:22775000-22800000,
chr21:18500000-18525000~~chr21:22775000-22800000,
chr21:21000000-21025000~~chr21:22775000-22800000,
chr21:21150000-21175000~~chr21:22775000-22800000,
chr21:21225000-21250000~~chr21:22775000-22800000,
chr21:21350000-21375000~~chr21:22775000-22800000,
chr21:21375000-21400000~~chr21:22775000-22800000,
chr21:21450000-21475000~~chr21:22775000-22800000,
chr21:21475000-21500000~~chr21:22775000-22800000,
chr21:21500000-21525000~~chr21:22775000-22800000,
chr21:21675000-21700000~~chr21:22775000-22800000,
chr21:21750000-21775000~~chr21:22775000-22800000,
chr21:21900000-21925000~~chr21:22775000-22800000,
chr21:21920929-21923014~~chr21:22791378-22793109,
chr21:21921038-21922969~~chr21:22791400-22793101,
chr21:21925000-21950000~~chr21:22775000-22800000,
chr21:22025000-22050000~~chr21:22775000-22800000,
chr21:22075000-22100000~~chr21:22775000-22800000,
chr21:22100000-22125000~~chr21:22775000-22800000,
chr21:22375000-22400000~~chr21:22775000-22800000,
chr21:22425000-22450000~~chr21:22775000-22800000,
chr21:22525000-22550000~~chr21:22775000-22800000,
chr21:22574322-22576128~~chr21:22791315-22793094,
chr21:22574346-22576088~~chr21:22791375-22793053,
chr21:22574494-22576035~~chr21:22791361-22792986,
chr21:22775000-22800000~~chr21:23000000-23025000,
chr21:22775000-22800000~~chr21:23375000-23400000,
chr21:22775000-22800000~~chr21:23400000-23425000,
chr21:22775000-22800000~~chr21:23950000-23975000,
chr21:22775000-22800000~~chr21:25025000-25050000,
chr21:22775000-22800000~~chr21:25300000-25325000,
chr21:22775000-22800000~~chr21:32575000-32600000,
chr21:22791492-22794100~~chr21:23015838-23017548,