- Basic information
- CohesinDB ID: CDBP00414898
- Locus: chr21-22884517-22885537
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Data sourse: GSE138405, GSE25021, GSE85526, ENCSR000EDE, GSE126990, GSE108869, ENCSR000ECS
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Cell type: MCF-7, HeLa-S3, Hela-Kyoto, HEKn
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.956
- Subunit: SA1,Rad21,SMC1,SA2,SMC3
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: TSS,TES
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
25% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 74%,
"7_Enh": 10%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: PGR, NANOG, POU5F1, SMAD3, MAFF, STAT1, FOXA1, HOXB13, HOXC5, RELA, CREBBP, JUNB, MYC, GR, RAD21, CHD7, DAXX, PBX4, ARNT, HIF1A, OTX2, GATA3, STAT3, MAX, FOXM1, FOS, RCOR1, NR3C1, TEAD1, TCF7L2, PIAS1, ESR1, GRHL2, NFKB1, EBF3, JUN, EP300, SP1, BAF155, AR, KDM5A, DPF2, YAP1, GATA2, EGLN2, ZHX1, BRD4, JUND, TEAD4, TFAP2C
- Target gene symbol (double-evidenced CRMs): NCAM2
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 9
- Related genes and loops
- Related gene:
ENSG00000154654,
- Related loop:
chr21:21225000-21250000~~chr21:22875000-22900000,
chr21:21500000-21525000~~chr21:22875000-22900000,
chr21:22175000-22200000~~chr21:22875000-22900000,
chr21:22550000-22575000~~chr21:22875000-22900000,
chr21:22625000-22650000~~chr21:22875000-22900000,
chr21:22725000-22750000~~chr21:22875000-22900000,
chr21:22875000-22900000~~chr21:22975000-23000000,
chr21:22875000-22900000~~chr21:23000000-23025000,
chr21:22875000-22900000~~chr21:23100000-23125000,
chr21:22875000-22900000~~chr21:23150000-23175000,
chr21:22875000-22900000~~chr21:23375000-23400000,
chr21:22875000-22900000~~chr21:23875000-23900000,