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Basic information

CohesinDB ID: CDBP00414898

Locus: chr21-22884517-22885537

Data sourse: GSE138405, GSE25021, GSE85526, ENCSR000EDE, GSE126990, GSE108869, ENCSR000ECS

Cell type: MCF-7, HeLa-S3, Hela-Kyoto, HEKn

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 2% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.956

Subunit: SA1,Rad21,SMC1,SA2,SMC3

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: TSS,TES

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 25% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 74%, "7_Enh": 10%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: PGR, NANOG, POU5F1, SMAD3, MAFF, STAT1, FOXA1, HOXB13, HOXC5, RELA, CREBBP, JUNB, MYC, GR, RAD21, CHD7, DAXX, PBX4, ARNT, HIF1A, OTX2, GATA3, STAT3, MAX, FOXM1, FOS, RCOR1, NR3C1, TEAD1, TCF7L2, PIAS1, ESR1, GRHL2, NFKB1, EBF3, JUN, EP300, SP1, BAF155, AR, KDM5A, DPF2, YAP1, GATA2, EGLN2, ZHX1, BRD4, JUND, TEAD4, TFAP2C

Target gene symbol (double-evidenced CRMs): NCAM2

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 9

Related genes and loops

Related gene: ENSG00000154654,

Tools:

Assay

refGene

Ruler

Cohesin site CDBP00414898

CDBP00414898 regulated genes

Related cohesin loop

Deatailed information for cohesin site CDBP00414898

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