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Basic information

CohesinDB ID: CDBP00414899

Locus: chr21-22891231-22893226

Data sourse: GSE138405, GSE101921, ENCSR000EDE, GSE126990, GSE108869, ENCSR000ECS

Cell type: HeLa-S3, Hela-Kyoto, HCAEC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 2% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.967

Subunit: SA1,Rad21,SMC1,SA2,SMC3

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intergenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 25% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 77%, "7_Enh": 10%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: FOXO1, CHD8, GTF2B, DUX4, SMAD3, MAFF, FOXA1, TWIST1, PAX6, RELA, NEUROD1, JUNB, CHD7, PRDM1, LHX2, PBX4, OTX2, GABPA, STAT3, TAL1, FOS, NR3C1, CEBPB, TEAD1, CEBPD, ETV1, TCF7L2, EZH2, SETDB1, EBF3, CTCF, ELF3, JUN, EP300, SPI1, GATA6, GATA2, FLI1, BRD4, JUND, CLOCK, SMC1, MRTFB, SMC3, STAG2

Target gene symbol (double-evidenced CRMs): NCAM2

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 28

Related genes and loops

Related gene: ENSG00000154654,

eachgene

Deatailed information for cohesin site CDBP00414899