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Basic information

CohesinDB ID: CDBP00414931

Locus: chr21-23131040-23132062

Data sourse: ENCSR000BLD, GSE206145-GSE177045, GSE104888, ENCSR230ZWH, GSE72082, GSE126634, ENCSR000BLY, ENCSR404BPV, GSE105028, GSE121355, GSE25021, GSE108869, ENCSR917QNE, GSE115602, ENCSR000BTU, GSE93080, ENCSR000DZP, ENCSR000EAC, GSE67783, GSE115250, GSE138405, GSE76893, GSE101921, GSE152721, GSE112028, GSE130135, ENCSR703TNG, GSE116344, GSE138105, GSE145327, GSE94872, ENCSR000EEG, ENCSR000ECE, ENCSR000EHX, GSE97394, ENCSR000BTQ, GSE105004, GSE131956, GSE129526, ENCSR000EDE, GSE68388, GSE126990, GSE50893, ENCSR000ECS, GSE38411

Cell type: RH4, GM2610, SLK, HSPC, Liver, TC-32, HuCC-T1, H9-hESC, GM2630, Ishikawa, HeLa-S3, GM2255, BCBL-1, GM18486, GM18526, H1-hESC, SNYDER, GM12878, GM12891, GM2588, GBM39, SK-N-SH, GM19239, HeLa-Tet-On, GM19099, HUES64, MCF-7, Hela-Kyoto, HCT-116, MCF-10A, HEK293T, Hep-G2, Neurons-H1, HUVEC, HCAEC, GM19238, HeLa, TC-71, HAP1

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 20% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.567

Subunit: SA1,Rad21,SMC1,SA2,SMC3

CTCF binding site: CTCF CTCF motif: False

Genomic location: TES

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 23% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 84%, "9_Het": 12%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: RUNX1, CHD8, SMC1A, FOXA2, NKX2-2, ZNF660, CBX1, STAG2, FOXA1, SRF, TRIM22, HOXB13, SMARCC1, MYC, CTCFL, RAD21, PBX4, ARNT, PROX1, NKX2-1, GATA3, SMC3, TAL1, MAX, CEBPB, TEAD1, CREB1, PIAS1, ESR1, ELF3, JUN, CTCF, AR, GATA2, EGLN2, IRF4, FLI1, BRD4, SMC1, TEAD4, STAG1

Target gene symbol (double-evidenced CRMs): .

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 19

Related genes and loops

Related gene:

eachgene

Deatailed information for cohesin site CDBP00414931