- Basic information
- CohesinDB ID: CDBP00414933
- Locus: chr21-23152070-23152626
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Data sourse: ENCSR000BLD, ENCSR000BTQ, ENCSR000BTU, GSE72082, GSE138405, GSE25021, ENCSR000BLY, ENCSR404BPV, ENCSR000EHW, GSE105028, ENCSR000ECE, ENCSR000EHX, ENCSR198ZYJ, GSE138105, ENCSR703TNG, GSE126990
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Cell type: MCF-7, H1-hESC, Hela-Kyoto, Neurons-H1, SLK, Ishikawa, SK-N-SH, H9-hESC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 6% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.911
- Subunit: SMC3,Rad21,SA2,SA1
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CTCF binding site: CTCF
CTCF motif: True
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
23% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 92%,
"9_Het": 8%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: NANOG, FOXA2, ZSCAN16, FOXA1, HOXB13, ERG, RELA, JUNB, AHR, RAD21, PRDM1, PBX4, HIF1A, GABPA, NKX3-1, TLE3, CREB1, PIAS1, ETV1, ESR1, CTCF, EP300, BAF155, SPI1, AR, GATA2, REST, ARID1A, BRD4, FOXP1, SMC3, STAG1, TFAP2C
- Target gene symbol (double-evidenced CRMs): NCAM2
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 6
- Related genes and loops
- Related gene:
ENSG00000154654,
- Related loop:
chr21:21000000-21025000~~chr21:23150000-23175000,
chr21:22350000-22375000~~chr21:23150000-23175000,
chr21:22625000-22650000~~chr21:23150000-23175000,
chr21:22875000-22900000~~chr21:23150000-23175000,
chr21:22975000-23000000~~chr21:23150000-23175000,
chr21:23125000-23150000~~chr21:23225000-23250000,
chr21:23125000-23150000~~chr21:23250000-23275000,
chr21:23125000-23150000~~chr21:23375000-23400000,
chr21:23125000-23150000~~chr21:23400000-23425000,
chr21:23125000-23150000~~chr21:23575000-23600000,
chr21:23125000-23150000~~chr21:23700000-23725000,
chr21:23125000-23150000~~chr21:23725000-23750000,
chr21:23125000-23150000~~chr21:23950000-23975000,
chr21:23125000-23150000~~chr21:25025000-25050000,
chr21:23125000-23150000~~chr21:25300000-25325000,
chr21:23125000-23150000~~chr21:25375000-25400000,
chr21:23150000-23175000~~chr21:23250000-23275000,
chr21:23150000-23175000~~chr21:23350000-23375000,
chr21:23150000-23175000~~chr21:23375000-23400000,
chr21:23150000-23175000~~chr21:23475000-23500000,
chr21:23150000-23175000~~chr21:23700000-23725000,