- Basic information
- CohesinDB ID: CDBP00414934
- Locus: chr21-23160688-23161440
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Data sourse: ENCSR000BLD, GSE72082, ENCSR000BLY, GSE105028, GSE25021, GSE108869, ENCSR000BTU, GSE138405, GSE76893, GSE101921, GSE138105, ENCSR703TNG, GSE94872, ENCSR000EHW, ENCSR000EHX, GSE97394, ENCSR000BTQ, GSE105004, ENCSR000EDE, GSE126990, ENCSR000ECS
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Cell type: MCF-7, H1-hESC, Hela-Kyoto, SLK, Ishikawa, HUVEC, HCAEC, HeLa-S3, HeLa, HUES64, SK-N-SH, H9-hESC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 8% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.867
- Subunit: SA1,Rad21,SMC1,SA2,SMC3
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CTCF binding site: CTCF
CTCF motif: True
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
23% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 94%,
"9_Het": 6%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: SMC1A, FOXA2, TOP2A, STAG2, FOXA1, SRF, HOXB13, ERG, ONECUT1, RAD21, PRDM9, NKX3-1, CREB1, PIAS1, ESR1, CTCF, BAF155, AR, GATA2, ZNF182, EGLN2, SMC1, SMC3, STAG1
- Target gene symbol (double-evidenced CRMs): NCAM2
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 16
- Related genes and loops
- Related gene:
ENSG00000154654,
- Related loop:
chr21:21000000-21025000~~chr21:23150000-23175000,
chr21:22350000-22375000~~chr21:23150000-23175000,
chr21:22625000-22650000~~chr21:23150000-23175000,
chr21:22875000-22900000~~chr21:23150000-23175000,
chr21:22975000-23000000~~chr21:23150000-23175000,
chr21:23150000-23175000~~chr21:23250000-23275000,
chr21:23150000-23175000~~chr21:23350000-23375000,
chr21:23150000-23175000~~chr21:23375000-23400000,
chr21:23150000-23175000~~chr21:23475000-23500000,
chr21:23150000-23175000~~chr21:23700000-23725000,