- Basic information
- CohesinDB ID: CDBP00414935
- Locus: chr21-23162547-23162838
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Data sourse: GSE101921, GSE25021
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Cell type: MCF-7, HCAEC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 0% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: SA1,SA2
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
23% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 86%,
"9_Het": 11%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, FOSL1, PGR, FOXA2, XBP1, MAFF, DUX4, SMAD3, FOXA1, ERG, HOXC5, RELA, JUNB, MYC, PBX4, HIF1A, NKX2-1, GABPA, TAL1, MAX, FOS, CDK8, CEBPB, PDX1, CEBPD, ESR1, PKNOX1, TBX5, NFKB1, JUN, NUP98-HOXA9, MAFK, EP300, T, AR, IRF1, GATA2, FLI1, JUND, STAG2
- Target gene symbol (double-evidenced CRMs): NCAM2
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 5
- Related genes and loops
- Related gene:
ENSG00000154654,
- Related loop:
chr21:21000000-21025000~~chr21:23150000-23175000,
chr21:22350000-22375000~~chr21:23150000-23175000,
chr21:22625000-22650000~~chr21:23150000-23175000,
chr21:22875000-22900000~~chr21:23150000-23175000,
chr21:22975000-23000000~~chr21:23150000-23175000,
chr21:23150000-23175000~~chr21:23250000-23275000,
chr21:23150000-23175000~~chr21:23350000-23375000,
chr21:23150000-23175000~~chr21:23375000-23400000,
chr21:23150000-23175000~~chr21:23475000-23500000,
chr21:23150000-23175000~~chr21:23700000-23725000,