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Basic information

CohesinDB ID: CDBP00414962

Locus: chr21-23402490-23404003

Data sourse: GSE115250, GSE138405, GSE126634, ENCSR000BLY, ENCSR000EHW, GSE152721, ENCSR000EHX

Cell type: TC-32, Hela-Kyoto, HAP1, SK-N-SH

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 2% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.956

Subunit: SMC3,Rad21,SA2,SMC1

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: TES,Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 26% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 90%, "9_Het": 9%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: FOXO1, PGR, FOXA2, NKX2-2, MYCN, CHD2, DUX4, FOXA1, FOXF1, HOXB13, TWIST1, KDM1A, TFAP4, ERG, RARA, YY1, NFIC, MYC, GR, ISL1, RAD21, GRHL3, ARNT, PBX4, GATA3, PBX3, PAX5, RCOR1, HAND2, TLE3, NR3C1, ESRRA, TEAD1, PIAS1, KDM5B, ESR1, PITX3, EBF3, PHOX2B, NUP98-HOXA9, TCF12, EP300, BAF155, AR, GATA2, EGLN2, MAML3, MXI1, BRD4, JUND, FOXP1, TEAD4, TBX2, PDX1

Target gene symbol (double-evidenced CRMs): NCAM2

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 20

Related genes and loops

Related gene: ENSG00000154654,

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Deatailed information for cohesin site CDBP00414962